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What Does My Liver Function Test Result Indicate?
Question: last week i went hospital reg hbsag test because six month before my wife have hbsag positive result during pregnancy delivery time.at that time doctor are advised to check hbsag testlevel for both husband and wife. i.e i went to hospital and doctors are instructed to me to take blood test and hiv and also liver function test . the test result are HBsAg -Non- reactive Anti- HBc-non reactive hiv-non reactive but liver function test shows that sgptand sgot values are high then doctor are advised to me to take scan . now my question is whether am hepatitis virus infected or not next what can i do further levels?
Brief Answer:
Hepatitis B, rise of liver enzymes
Detailed Answer:
Hi,
Thank you for your query. I can understand your concerns.
Anti-HBc is readily demonstrable in serum, begin within the first 1–2 weeks after the appearance of HBsAg and preceding detectable levels of anti-HBs by weeks to months. Occasionally a gap of several weeks or longer may separate the disappearance of HBsAg and the appearance of anti-HBs.During this "gap" or "window" period anti-HBc may represent the only serologic evidence of current or recent HBV infection,Generally, in persons who have recovered from hepatitis B, anti-HBs and anti-HBc persist indefinitely.
Since you are negative for both HBsAg & Anti- HBc, you are not having Hepatitis B virus infection.
Since your SGOT& SGPT values are high, your doctor as advised liver imaging either Ultrasonography or CT scan of abdomen as fatty liver can cause steato-hepatitis and cause rise of SGOT & SGPT values.
Regards
Dr. T.K. Biswas M.D. XXXXXXX
Hepatitis B, rise of liver enzymes
Detailed Answer:
Hi,
Thank you for your query. I can understand your concerns.
Anti-HBc is readily demonstrable in serum, begin within the first 1–2 weeks after the appearance of HBsAg and preceding detectable levels of anti-HBs by weeks to months. Occasionally a gap of several weeks or longer may separate the disappearance of HBsAg and the appearance of anti-HBs.During this "gap" or "window" period anti-HBc may represent the only serologic evidence of current or recent HBV infection,Generally, in persons who have recovered from hepatitis B, anti-HBs and anti-HBc persist indefinitely.
Since you are negative for both HBsAg & Anti- HBc, you are not having Hepatitis B virus infection.
Since your SGOT& SGPT values are high, your doctor as advised liver imaging either Ultrasonography or CT scan of abdomen as fatty liver can cause steato-hepatitis and cause rise of SGOT & SGPT values.
Regards
Dr. T.K. Biswas M.D. XXXXXXX
Above answer was peer-reviewed by :
Dr. Bhagyalaxmi Nalaparaju
Respected Sir:
am alcoholic drinker regularly.
sir what can i do for my wife feature treatment and my position ?
next coming to my child after born doctors are immediately vaccinated against hepatitis injection my question is whether is there any problem for my child
thank u sir
am alcoholic drinker regularly.
sir what can i do for my wife feature treatment and my position ?
next coming to my child after born doctors are immediately vaccinated against hepatitis injection my question is whether is there any problem for my child
thank u sir
Brief Answer:
HBV infection,vaccination
Detailed Answer:
Hi,
Thank you for your query. I can understand your concerns.
Your wife has to undergo further tests like HBeAg ( a qualitative marker) and HBV DNA (a quantitative marker) to determine active viral replication( replicative stage of HBV infection)or she is just inactive HBV carrier.Treatment will be decided according to the results.
If you(sexual contacts of HBsAg carriers) are not vaccinated ,postexposure prophylaxis with a combination of Hepatitis B Immune Globulin (HBIG) -for rapid achievement of high-titer circulating anti-HBs and hepatitis B vaccine is recommended with three IM (deltoid, not gluteal) injections of hepatitis B vaccine at 0, 1, and 6 months .
You also have to use protective sheath till your vaccine course is completed.
For perinatal exposure of infants born (your child) to HBsAg-positive mothers, a single dose of HBIG, 0.5 mL, should be administered IM in the thigh immediately after birth, followed by a complete course of three injections of recombinant hepatitis B vaccine to be started within the first 12 hours of life.
Regards
Dr. T.K. Biswas M.D. XXXXXXX
HBV infection,vaccination
Detailed Answer:
Hi,
Thank you for your query. I can understand your concerns.
Your wife has to undergo further tests like HBeAg ( a qualitative marker) and HBV DNA (a quantitative marker) to determine active viral replication( replicative stage of HBV infection)or she is just inactive HBV carrier.Treatment will be decided according to the results.
If you(sexual contacts of HBsAg carriers) are not vaccinated ,postexposure prophylaxis with a combination of Hepatitis B Immune Globulin (HBIG) -for rapid achievement of high-titer circulating anti-HBs and hepatitis B vaccine is recommended with three IM (deltoid, not gluteal) injections of hepatitis B vaccine at 0, 1, and 6 months .
You also have to use protective sheath till your vaccine course is completed.
For perinatal exposure of infants born (your child) to HBsAg-positive mothers, a single dose of HBIG, 0.5 mL, should be administered IM in the thigh immediately after birth, followed by a complete course of three injections of recombinant hepatitis B vaccine to be started within the first 12 hours of life.
Regards
Dr. T.K. Biswas M.D. XXXXXXX
Note: For more detailed guidance, please consult an Internal Medicine Specialist, with your latest reports. Click here..
Above answer was peer-reviewed by :
Dr. Vinay Bhardwaj
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