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What Does Antinuclear Antibodies Test Report Of 1:40 Indicate?
Question: Question related to ANTI-NUCLEAR AB-IFA, HEP2, SERUM
What does the below values interpret:
ANTINUCLEAR ANTIBODIES POSITIVE
METHOD : IMMUNOFLUORESCENCE MICROSCOPY
PRIMARY DILUTION 1:40
METHOD : IMMUNOFLUORESCENCE MICROSCOPY
PRIMARY INTENSITY ON IF 1+
METHOD : IMMUNOFLUORESCENCE MICROSCOPY
ANA PATTERN SPECKLED
METHOD : IMMUNOFLUORESCENCE MICROSCOPY
END POINT TITRE 1:40
What does the below values interpret:
ANTINUCLEAR ANTIBODIES POSITIVE
METHOD : IMMUNOFLUORESCENCE MICROSCOPY
PRIMARY DILUTION 1:40
METHOD : IMMUNOFLUORESCENCE MICROSCOPY
PRIMARY INTENSITY ON IF 1+
METHOD : IMMUNOFLUORESCENCE MICROSCOPY
ANA PATTERN SPECKLED
METHOD : IMMUNOFLUORESCENCE MICROSCOPY
END POINT TITRE 1:40
Brief Answer:
Value less than or equal to 1:40 is negative.
Detailed Answer:
Hello XXXXXXX
Thanks for writing to HCM
I have gone through your reports in detail.
An ANA test detects antinuclear antibodies in blood.It is generally indicated in autoimmune disorders like lupus,rheumatoid arthritis,scleroderma etc.
Titre value less than or equal to 1:40 dilution is considered as negative.
However some laboratory use 1:20 as cut-off criteria.
According to the Lupus Foundation of XXXXXXX there is no universal normal range for ANA titers because the definition of "normal" varies from lab to lab.
Positive test by itself is not diagnostic of autoimmune disease.
Physician should rely on numerous criteria such as patient symptoms,physical examination and additional blood work to confirm diagnosis.
Get well soon.
Hope I have answered your question.
Further queries are most welcome.
Take Care
Dr.Indu XXXXXXX
Value less than or equal to 1:40 is negative.
Detailed Answer:
Hello XXXXXXX
Thanks for writing to HCM
I have gone through your reports in detail.
An ANA test detects antinuclear antibodies in blood.It is generally indicated in autoimmune disorders like lupus,rheumatoid arthritis,scleroderma etc.
Titre value less than or equal to 1:40 dilution is considered as negative.
However some laboratory use 1:20 as cut-off criteria.
According to the Lupus Foundation of XXXXXXX there is no universal normal range for ANA titers because the definition of "normal" varies from lab to lab.
Positive test by itself is not diagnostic of autoimmune disease.
Physician should rely on numerous criteria such as patient symptoms,physical examination and additional blood work to confirm diagnosis.
Get well soon.
Hope I have answered your question.
Further queries are most welcome.
Take Care
Dr.Indu XXXXXXX
Above answer was peer-reviewed by :
Dr. Chakravarthy Mazumdar
why 1:40 is mentioned in report as positive and numerous links over internet talks it as positive test. sorry to sound stupid
Brief Answer:
Please find detail answer below.
Detailed Answer:
Hello XXXXXXX
Thanks for writing to HCM
I can understand your doubt.
As we discussed earlier,cut-off criteria varies with laboratory.
I quoted my range from authentic e-medicine site.
1 : 40 is not a very strong titer to confirm the disease.
Probably,your laboratory has 1: 40 as cut-off criteria.So,you can rely this.But even then it is borderline value and disease should be correlated by other means like symptoms,physical examination, additional blood work up etc.
Get well soon.
Hope I have answered your question.
Further queries are most welcome.
Take Care
Dr.Indu XXXXXXX
Please find detail answer below.
Detailed Answer:
Hello XXXXXXX
Thanks for writing to HCM
I can understand your doubt.
As we discussed earlier,cut-off criteria varies with laboratory.
I quoted my range from authentic e-medicine site.
1 : 40 is not a very strong titer to confirm the disease.
Probably,your laboratory has 1: 40 as cut-off criteria.So,you can rely this.But even then it is borderline value and disease should be correlated by other means like symptoms,physical examination, additional blood work up etc.
Get well soon.
Hope I have answered your question.
Further queries are most welcome.
Take Care
Dr.Indu XXXXXXX
Above answer was peer-reviewed by :
Dr. Chakravarthy Mazumdar
Answered by
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