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What Does Monoclonal Gammopathy With IgM Kappa Paraprotein Indicate?

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Posted on Mon, 9 Jun 2014
Question: I have been tolf thru blood tests that I have monoclonal igm kappa protein. my igm is 1970. now what?
but I also have active hep c...even those years of trying to kick it!
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Answered by Dr. Chakravarthy Mazumdar (7 hours later)
Brief Answer:
Why were they done initialy

Detailed Answer:
Hi,

We do not know why was the test done in the initial place. Do you have any symptoms of anemia, enlarged liver and spleen etc?

Monoclonal Gammopathy with IgM kappa paraprotein is known. There are a lot of cases, close to 60%, where there is no cause found also called Monoclonal Gammopathy of Undeterminate Significance called IgM MGUS.

Probably the bone marrow needling for microscopy is the next step to check if there are lymphoplasmocyte infiltrates.

I suggest you to see an Hematologist the next for further steps.
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Above answer was peer-reviewed by : Dr. Aparna Kohli
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Answered by
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Dr. Chakravarthy Mazumdar

General & Family Physician

Practicing since :2004

Answered : 2242 Questions

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What Does Monoclonal Gammopathy With IgM Kappa Paraprotein Indicate?

Brief Answer: Why were they done initialy Detailed Answer: Hi, We do not know why was the test done in the initial place. Do you have any symptoms of anemia, enlarged liver and spleen etc? Monoclonal Gammopathy with IgM kappa paraprotein is known. There are a lot of cases, close to 60%, where there is no cause found also called Monoclonal Gammopathy of Undeterminate Significance called IgM MGUS. Probably the bone marrow needling for microscopy is the next step to check if there are lymphoplasmocyte infiltrates. I suggest you to see an Hematologist the next for further steps.