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What Do Elevated ESR And CRP Levels Indicate?

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Posted on Wed, 1 Jul 2015
Question: My sed rate is 22 it was previously 16 in march. My crp is 14.7. I'm a 46 year old male . 6'2" 245 lbs. My joints fill stiff with headaches. But rest of labs okay. I have small infection on tooth and have been taking amox clav for 7 days 4 days before blood test

My joints are stiff, do popping sound, a little soar. My labs are available at
my.memorialhermann.org
login : YYYY@YYYY
password : XXXX

Check all labs button to bring up sorry.
doctor
Answered by Dr. Anil Parth Desai (57 minutes later)
Brief Answer:
Elevated ESR and CRP indicate chronic systemic inflammatory process.

Detailed Answer:
Hello sir,
I did review your concern.
I also did a detailed review of all of your previous laboratory reports.
Your reports have been significant for blood in urine in form of isolated microscopic hematuria.
This is seen in bladder condition like stones, infections, unwanted growths or kidney conditions like IgA nephropathy, Alport syndrome, rheumatoid arthritis.
Apart from that , there have been occasional instances of mild neutrophilia with elevated wbc count suggestive of inflammatory/infectious process.
Now the recent elevation in CRP and ESR supports it.
With your stiff joints, headache and blood in urine I would recommend a workup for systemic inflammatory joint disease like rheumatoid arthritis.

1)As I could see the result for CCP is pending and it is a specific test for rheumatoid arthritis. Also ANA is being tested for autoimmune disorder.
2)i would also recommend a xray of your stiff joints with this.
3)Apart from this, In the near future if the blood in urine continues I would recommend a CT urography to rule out any local renal conditions.

I hope this helps.
Let me know if you have any more questions or concerns.
Wish you all the best
sincerely,
Dr Parth Desai
Note: Do you have more questions on diagnosis or treatment of blood disorders? Ask An Expert/ Specialist Now

Above answer was peer-reviewed by : Dr. Vinay Bhardwaj
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Answered by
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Dr. Anil Parth Desai

Pathologist and Microbiologist

Practicing since :2009

Answered : 593 Questions

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What Do Elevated ESR And CRP Levels Indicate?

Brief Answer: Elevated ESR and CRP indicate chronic systemic inflammatory process. Detailed Answer: Hello sir, I did review your concern. I also did a detailed review of all of your previous laboratory reports. Your reports have been significant for blood in urine in form of isolated microscopic hematuria. This is seen in bladder condition like stones, infections, unwanted growths or kidney conditions like IgA nephropathy, Alport syndrome, rheumatoid arthritis. Apart from that , there have been occasional instances of mild neutrophilia with elevated wbc count suggestive of inflammatory/infectious process. Now the recent elevation in CRP and ESR supports it. With your stiff joints, headache and blood in urine I would recommend a workup for systemic inflammatory joint disease like rheumatoid arthritis. 1)As I could see the result for CCP is pending and it is a specific test for rheumatoid arthritis. Also ANA is being tested for autoimmune disorder. 2)i would also recommend a xray of your stiff joints with this. 3)Apart from this, In the near future if the blood in urine continues I would recommend a CT urography to rule out any local renal conditions. I hope this helps. Let me know if you have any more questions or concerns. Wish you all the best sincerely, Dr Parth Desai