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What Causes Tingling Sensation In The Legs While On Valium?

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Posted on Mon, 12 Jun 2017
Question: I have creepy crawly, burning skin sensations on my legs, feet and a few times my hands. I've had cold feelings on my upper arms and burning/tingling feeling on my face. I have no weakness, numbness or anything else. Dr. did a neuro. exam and said it's not MS but not sure what it is. I had this 6 years ago and had an MRI, EMG, ENG, EVP and all were normal. I was using Valium and getting off of it so we attributed all these symptoms to that. I was finally able to stop the Valium completely 15 months ago and have had no symptoms until 3 weeks ago these came back. According to a Benzo site this can happen after 15 months but I'm not convinced. Any thoughts? I am having another MRI on May 30th.
doctor
Answered by Dr. Olsi Taka (2 hours later)
Brief Answer:
Anxiety to be considered.

Detailed Answer:
I read your question carefully and I understand your concern.

I am not sure that the MRI you are having is going to be of any benefit, since these are the same symptoms you had in the past with a normal MRI this one is probably going to com back normal as well. Furthermore those widespread symptoms do not correspond to a specific brain or spinal cord area. MS might be considered as it may affect multiple areas, but the first MRI would detect it and also there would be other symptoms not the same ones over and over again.

If there is a damage of the nervous system it would be more likely in the peripheral nervous system, if I were to repeat an exam it would be EMG/ENG. In addition there are forms of peripheral nerve damage, like smal fiber neuropathy where EMG/ENG studies may not detect any damage, only nerve biopsy can. So that would be the only neurological condition I would consider to investigate.

However I would retain as much more likely the possibility of the symptoms being simply due to anxiety. Anxiety may commonly manifest with such abnormal sensations and the relationship with the withdrawal from Valium, an antianxiety medication, would be in favor of that. I believe that there is an underlying anxiety disorder with periods of exacerbation like the present symptoms. Judging from your age the appearance of the symptoms corresponds to the period of menopause which with its hormonal fluctuations may contribute as well.
If it is a chronic issue I would suggest antianxiety medication, not benzodiazepines which create dependence and tolerance, but antidepressants.

I remain at your disposal for other questions.
Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar
doctor
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Follow up: Dr. Olsi Taka (28 minutes later)
Thanks for the reply. I have considered anxiety but....at the time these symptoms present themselves I am feeling NO anxiety. Things in my life couldn't be better.
I was given Valium originally because of insomnia which I believe was brought on by menopause - then it gave me weird symptoms then took 4 years to get off of it with EXTREME symptoms.

Do you really think this could be symptoms of withdrawal? The Benzo site says it's not unusual but I just can't believe it.

In addition to creepy crawly/slight burning on my shins today I have freezing fingers and toes but very sweaty palms and feet. Also had this 6 years ago.

Thank you for calming me somewhat about MS but I'm still very concerned and would like to know what exactly is going on.

Thanks, XXXXXXX
doctor
Answered by Dr. Olsi Taka (38 minutes later)
Brief Answer:
Read below

Detailed Answer:
Regarding the fact that things are going well in your life I would like to point out that anxiety doesn't have to be in the setting of a stressful situation, it is a question of neurotransmitter imbalance in the brain affecting mood. Long term benzodiazepine use may play a role, it does alter neurotransmitter balance, affecting levels also of other neurotransmitters such as serotonin and norepinephrine. As a result its withdrawal may disrupt that delicate balance and time be needed to find a new state of equilibrium. So yes it can be related. In addition its use my have covered an underlying issue which has resurfaced now.

As for the cold sensations associated with sweaty palms, they can both be a manifestation of the sympathetic nervous system, responsible for the fight or flight reaction. So anxiety does explain it well (whether preexisting or triggered by benzodiazepine use).
However some other possibilities of those symptoms should be considered, not necessarily neurological ones, but also rheumatologic like lupus or arthritis and hormonal alterations, in particular the thyroid hormone. For that reason some routine blood tests should be done in that regard to search for those conditions like complete blood count, ESR, antinuclear antibodies, rheumatoid factor, liver and kidney function, electrolyte panel, thyroid function.

Let me know if I can furthr assist you.
Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar
doctor
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Follow up: Dr. Olsi Taka (24 minutes later)
Thank you. 6 years ago they tested for Lyme and Lupus. Last week they also took blood checking for all the conditions you mentioned which all came back normal so it looks like they are doing all the right things.
I guess I'm going to go with the Benzo use explanation right now and see how it goes. I'm hoping it just goes away since it was gone for about 14 months and now it's back to a lesser degree so far.

Thanks.
doctor
Answered by Dr. Olsi Taka (7 hours later)
Brief Answer:
Read below

Detailed Answer:
Yes they seem to be thorough in their testing. As I said before the benzos do play a role, but often it is a combination of things, a patient being more prone to anxiety, benzdiazepine alterations, hormonal changes after menopaus etc which may lea to such manifestations in a prone individual. But one thing you should feel reassured about, given the normal tests and the character of the symptoms there is no indication of any serious disease, meaning of something which may be life threatening or disabling in time.

Wishing you good health,
Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar
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Answered by
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Dr. Olsi Taka

Neurologist

Practicing since :2004

Answered : 3673 Questions

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What Causes Tingling Sensation In The Legs While On Valium?

Brief Answer: Anxiety to be considered. Detailed Answer: I read your question carefully and I understand your concern. I am not sure that the MRI you are having is going to be of any benefit, since these are the same symptoms you had in the past with a normal MRI this one is probably going to com back normal as well. Furthermore those widespread symptoms do not correspond to a specific brain or spinal cord area. MS might be considered as it may affect multiple areas, but the first MRI would detect it and also there would be other symptoms not the same ones over and over again. If there is a damage of the nervous system it would be more likely in the peripheral nervous system, if I were to repeat an exam it would be EMG/ENG. In addition there are forms of peripheral nerve damage, like smal fiber neuropathy where EMG/ENG studies may not detect any damage, only nerve biopsy can. So that would be the only neurological condition I would consider to investigate. However I would retain as much more likely the possibility of the symptoms being simply due to anxiety. Anxiety may commonly manifest with such abnormal sensations and the relationship with the withdrawal from Valium, an antianxiety medication, would be in favor of that. I believe that there is an underlying anxiety disorder with periods of exacerbation like the present symptoms. Judging from your age the appearance of the symptoms corresponds to the period of menopause which with its hormonal fluctuations may contribute as well. If it is a chronic issue I would suggest antianxiety medication, not benzodiazepines which create dependence and tolerance, but antidepressants. I remain at your disposal for other questions.