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What Causes Swollen Bleeding Lower Lip After Using Efudex?

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Posted on Fri, 9 Oct 2015
Question: I have been using Efudex on my face and lips for 5 weeks and my lower lip has become very swollen today and constantly weeps and bleeds.I am a long way from my primary care Dr and I did see a Dr in the ED of the local hospital 2 days ago and he said I need excision and plastic surgery.
Do I keep using Efudex ? I won't get back home till Tuesday to see my doc and Dr who prescribed cream I can see on Thursday.
doctor
Answered by Dr. Dr. Kakkar (1 hour later)
Brief Answer:
kindly upload an image;discontinue efudex for the time being

Detailed Answer:
Hello. Thank you for writing to us

I have gone through your query and I have noted down your concern.

I request you to kingly upload an Image so that I am able to guide you better. You may upload an Image either in "Reports Section" Or you may mail me at YYYY@YYYY with the subject line as Attention:Dr. Kakkar.
Efudex is topical 5-fluorouracil (5-FU) which is an anti-cancer drug and was probably prescribed for actinic cheilitis and actinic keratosis on face.
Fluorouracil can cause irritation/ inflammation and may present as edema, erosions, weeping, bleeding and crusting.
I suggest you to discontinue this cream for the time being.
You may rather use a moderately potent topical steroid e.g mometasone furoate 0.1% cream Or triamcinolone acetonide 0.1%, twice daily, over the affected area for next 3-5 days.
Protect from sun. Use a sunscreen.

Regards
Note: Hope the answers resolves your concerns, however for further guidance of skin related queries consult our Dermatologist.Click here to book a consultation

Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar
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Answered by
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Dr. Dr. Kakkar

Dermatologist

Practicing since :2002

Answered : 9612 Questions

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What Causes Swollen Bleeding Lower Lip After Using Efudex?

Brief Answer: kindly upload an image;discontinue efudex for the time being Detailed Answer: Hello. Thank you for writing to us I have gone through your query and I have noted down your concern. I request you to kingly upload an Image so that I am able to guide you better. You may upload an Image either in "Reports Section" Or you may mail me at YYYY@YYYY with the subject line as Attention:Dr. Kakkar. Efudex is topical 5-fluorouracil (5-FU) which is an anti-cancer drug and was probably prescribed for actinic cheilitis and actinic keratosis on face. Fluorouracil can cause irritation/ inflammation and may present as edema, erosions, weeping, bleeding and crusting. I suggest you to discontinue this cream for the time being. You may rather use a moderately potent topical steroid e.g mometasone furoate 0.1% cream Or triamcinolone acetonide 0.1%, twice daily, over the affected area for next 3-5 days. Protect from sun. Use a sunscreen. Regards