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What causes phelmorphic Sarcoma Tumor in the leg?

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Oncologist, Surgical
Practicing since : 2008
Answered : 576 Questions
Please tell what could cause my daughter to get a phelmorphic Sarcoma Tumor in her leg - size of a football?Can Stress cause this type of cancer, or overuse of the tumor leg?
Posted Sun, 2 Feb 2014 in Cancer
Answered by Dr. Rohan Khandelwal 17 minutes later
Brief Answer: Environmental & Genetic factors Detailed Answer: Dear Ma'am, Sorry to hear about your daughter's condition. Sarcomas can be of various types and there have been many risk factors implicated in the development of sarcomas. 1. Genetic mutations, which gradually add up, can lead to these lesions. Mutation in the p53 gene are quite common in these patients. 2. Smoking & Alcohol consumption can increase the risk of these cancers 3. Exposure to radiation These are some of the factors which can predispose to a sarcoma but it is very difficult to pinpoint one cause for your daughter's condition. She should be thoroughly investigated. MRI of the limb, Ct scan of the thorax and abdomen and a biopsy of the lesion. This should be followed by excision of the lesion and chemotherapy. Hoping for the best. Please feel free to clarify any other query.
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