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What Causes Hypermanic Episodes And Depression?
Question: my husband is on 15mg prednisolone a day. he had a hypermanic episode in April/May this year because of (at the time up to 50mg prednisolone a day) the cortisone. he's now suffering from severe depression and is having ect which doesn't seem to be working. he's had 11 treatments and doesn't seem a lot better. the last one his bp spiked to about 230 and they are now testing him for some sort of I think it was a tumour and something to do with the adrenal glands. I thought the name was something like XXXXXXX - chrome - something? Do you have any ideas what it would be?
the other drugs he's currently on are methotrexate (one dose p/week) because initially the prednisolone was administered for polymyalgia; and daily, quetiapine 50mg; amlodipine 5 mg (because his bp went up since ect); oxazepam 2 - 3 x 7.5mg; duloxetine 60mg.
the other drugs he's currently on are methotrexate (one dose p/week) because initially the prednisolone was administered for polymyalgia; and daily, quetiapine 50mg; amlodipine 5 mg (because his bp went up since ect); oxazepam 2 - 3 x 7.5mg; duloxetine 60mg.
Brief Answer:
Stroid induced Depression/Mania
Detailed Answer:
Good day,
Noted your concern. It is common for people to develop depression/mania while on high dose steroids. Since he is on steroids for a long time, it is difficult to wean him off quickly. Methotraxate is a steroid sparing drug and slowly we should try to taper steroids. You should meet an endocrinologist to do that.
The disease which you are mentioning is "Haemochromatosis: which is excess iron deposition in various organs. It has nothing to do with adrenal tumour. Are you mentioning about " Pheochromocytoma" ?? This is an adrenal tumour which can cause heart beat to go up and also cause high blood pressure.
Regards
Binu
Stroid induced Depression/Mania
Detailed Answer:
Good day,
Noted your concern. It is common for people to develop depression/mania while on high dose steroids. Since he is on steroids for a long time, it is difficult to wean him off quickly. Methotraxate is a steroid sparing drug and slowly we should try to taper steroids. You should meet an endocrinologist to do that.
The disease which you are mentioning is "Haemochromatosis: which is excess iron deposition in various organs. It has nothing to do with adrenal tumour. Are you mentioning about " Pheochromocytoma" ?? This is an adrenal tumour which can cause heart beat to go up and also cause high blood pressure.
Regards
Binu
Above answer was peer-reviewed by :
Dr. Chakravarthy Mazumdar
yes, yes, thank you . that's the name 'pheocromocytoma'. is there any connection with the likelihood of this and high dose steroids?
Brief Answer:
No relation
Detailed Answer:
No, Pheochromocytoma is a tumour in the adrenal which secrete adrenaline and noradrenaline. This has nothing to do with high dose steroids.
No relation
Detailed Answer:
No, Pheochromocytoma is a tumour in the adrenal which secrete adrenaline and noradrenaline. This has nothing to do with high dose steroids.
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Above answer was peer-reviewed by :
Dr. Chakravarthy Mazumdar
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