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What Causes CBC Test Result Indicate?

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Posted on Tue, 24 Mar 2015
Question: I am 33 years old female. Hypothyroidism and type 2 diabetic. TSH = 28.39, A1C 6.4. I recently had bloodwork (CBC) and most of it came back within normal range. The only ones that did not were:
Anisocytosis - result says "slight"
White blood count - 3.6
Schistocytes - "few"
Toxic Granulation - "few"

I'm aware of what needs to be done for the TSH but as far as the CBC results, Is this anything that needs attention?
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Answered by Dr. Kathy Robinson (59 minutes later)
Brief Answer:
not necessarily

Detailed Answer:
Hello and thank you for your question.
The finding on your CBC are very minor irregularities. You WBC is only slightly low and the anisocytosis, schistocytes and toxic granulations can come from many causes even an improperly handled blood sample. I would not worry about it but would ask your doctor to repeat the CBC in a few weeks and make sure that everything is back to normal.
Schistocytes may occur when blood cells are being destroyed for some reason. Anisocytes mean that cells are of different sizes as may occur in some anemias. Toxic granulations may occur in some inflammatory conditions like rheumatoid arthritis.
However, with the slight finding on your CBC I think these are unlikely and I suspect your next CBC will be normal.
Best just to get it checked out
Regards,
Dr. Robinson
Note: For more information on hormonal imbalance symptoms or unmanaged diabetes with other comorbid conditions, get back to us & Consult with an Endocrinologist. Click here to book an appointment.

Above answer was peer-reviewed by : Dr. Vinay Bhardwaj
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Answered by
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Dr. Kathy Robinson

General & Family Physician

Practicing since :1989

Answered : 3535 Questions

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What Causes CBC Test Result Indicate?

Brief Answer: not necessarily Detailed Answer: Hello and thank you for your question. The finding on your CBC are very minor irregularities. You WBC is only slightly low and the anisocytosis, schistocytes and toxic granulations can come from many causes even an improperly handled blood sample. I would not worry about it but would ask your doctor to repeat the CBC in a few weeks and make sure that everything is back to normal. Schistocytes may occur when blood cells are being destroyed for some reason. Anisocytes mean that cells are of different sizes as may occur in some anemias. Toxic granulations may occur in some inflammatory conditions like rheumatoid arthritis. However, with the slight finding on your CBC I think these are unlikely and I suspect your next CBC will be normal. Best just to get it checked out Regards, Dr. Robinson