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What Are The Side Effects Of Aleve?

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Posted on Wed, 13 Jan 2016
Question: I am taking 2 Aleve a day. I had total knee replacement in XXXXXXX I was told by a friend that there were no side effects with Aleve. Then I went to your web site and found that there are way too many side effects. The pain was in my big toe (which is no longer hurting without taking Aleve). I just bought more of it. It did work while my toe hurt. Should I worry about side effects?
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Answered by Dr. Michelle Gibson James (29 minutes later)
Brief Answer:
heart disease/stroke risk with high dose or very long history of use

Detailed Answer:
HI, thanks for using healthcare magic

All medications have potential side effects but the side effects occur in the minority not the majority of persons.

Some persons experience no effects at all, others only a few and others may have many effects.

Side effects are more common with high doses or if meds used for long period of time.

There is a risk of heart disease and stroke with aleve but this is greater if there is a recent previous heart attack or bypass or if a lot of risk factors are present (high blood pressure, smoking, high cholesterol, diabetes)

Your heart disease/stroke risk would decrease once you stop the medication. It can still be used intermittently if you need it.


There are also other side effects as well but these would occur at the time you are taking the medication eg constipation, reflux, abdominal pain, dizziness, headache, GI bleed
If these did not occur at the time you were using the medication and you have no lingering reflux/heartburn then you are likely ok with regard to these.

I hope this helps, feel free to ask any other questions
Note: For further queries, consult a joint and bone specialist, an Orthopaedic surgeon. Book a Call now.

Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar
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Answered by
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Dr. Michelle Gibson James

General & Family Physician

Practicing since :2001

Answered : 16808 Questions

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What Are The Side Effects Of Aleve?

Brief Answer: heart disease/stroke risk with high dose or very long history of use Detailed Answer: HI, thanks for using healthcare magic All medications have potential side effects but the side effects occur in the minority not the majority of persons. Some persons experience no effects at all, others only a few and others may have many effects. Side effects are more common with high doses or if meds used for long period of time. There is a risk of heart disease and stroke with aleve but this is greater if there is a recent previous heart attack or bypass or if a lot of risk factors are present (high blood pressure, smoking, high cholesterol, diabetes) Your heart disease/stroke risk would decrease once you stop the medication. It can still be used intermittently if you need it. There are also other side effects as well but these would occur at the time you are taking the medication eg constipation, reflux, abdominal pain, dizziness, headache, GI bleed If these did not occur at the time you were using the medication and you have no lingering reflux/heartburn then you are likely ok with regard to these. I hope this helps, feel free to ask any other questions