Get your Health question answered in 3 easy steps
A Doctor will be with you shortly
Ask a Doctor Now
189 Doctors are Online

Taking Azoran for ulcerative colitis. Have chronic pancreatitis. Is Azoran worsening my pancreatic condition?

User rating for this question
Very Good
Answered by

General & Family Physician
Practicing since : 2003
Answered : 115 Questions
Acute Pancreatitis in 2007 august.
Ulcerative colitis and Diabetes since 2008 XXXXXXX
On Azoran 50 mg now for UC. Recent pancreatic elastase stool test revealed chronic pancreatitis. Would like to know if Azoran is worsening my pancreatitis condition.
What are the other side effects of Azoran?
I also seem to be gradually losing weight. What kind of food and food supplement will help me gain weight.
Should I repeat pancreatic elastase stool test and how often?
Posted Tue, 11 Sep 2012 in Medicines and Side Effects
Answered by Dr. Mihail Iepure 2 hours later
Welcome to XXXXXXX
As an immunosuppressive antimetabolite Azathioprine (Azoran ) has many side effects, and may interfering with evolution of chronicle pancreatitis and in some cases worsening this condition, because peoples with normal pancreatic function while taking Azathioprine ( for another conditions ) may develop acute pancreatitis and vomiting, nausea, diarrhea with abdominal pain , that has been reported with hypersensitivity pancreatitis. The safety and efficacy of Azathioprine for the treatment of ulcerative colitis have not been established. Mainly side effects of Azathioprine are Hematologic ( leukopenia, thrombocytopenia, and anemia); Gastrointestinal (nausea, vomiting, diarrhea, anorexia and chronic malabsorption syndrome; Risk of infections and malignancy( lymphoma ); Hepatotoxicity (elevations in alkaline phosphatase, bilirubin, and/or serum transaminases, cholestatic jaundice, hepatitis ); Hypersensitivity ( rash, fever, malaise, vasculitis, hypotension ). I would recommend you periodically repeat complete blood count, liver function test to detect /prevent adverse effect of this drug.
You lost weight due to malabsorbtion syndrome as a effect of chronicle pancreatitis and side effect of azoran. In case of chronicle pancreatitis are prescribed low – fat diets with general considerations: Do not eat large meals at a time, rather go for small frequent meals ,avoid : concentrated sweets and desserts, caffeine and gas-forming food items, margarine, butter, bacons, alcohol, smoking, spicy food, you may include: soybeans ,light chicken soups or vegetable soups frequently, XXXXXXX leafy vegetables, fruit juice.
Elastase stool test you may repeat every three weeks.
Hope this helps and I have answered your query. If you have additional queries don’t hesitate to ask.

Best Regards,

Above answer was peer-reviewed by
Share on Facebook
Share on Twitter
Share on Google+
Question is related to

The user accepted the expert's answer

Ask an Internal Med Specialist

© Ebix, Inc. All Rights Reserved.
All the information, content and live chat provided on the site is intended to be for informational purposes only, and not a substitute for professional or medical advice. You should always speak with your doctor before you follow anything that you read on this website. Any health question asked on this site will be visible to the people who browse this site. Hence, the user assumes the responsibility not to divulge any personally identifiable information in the question. Use of this site is subject to our Terms & Conditions
Already Rated.
Your rating:

Ask a Doctor