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Suggest Treatment For Renal Dysfunction

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Posted on Fri, 17 Oct 2014
Question: Lisinopril caused dry cough, Diovan raised the Creatinine and Bun. Any other ARB that you would recommend ?
doctor
Answered by Dr. Prabhakar C Koregol (2 hours later)
Brief Answer:
Generally no

Detailed Answer:
If you have experienced renal dysfunction that needed discontinuation of the drug, then all the drugs of same class should be avoided unless there is compelling indications. As there are multiple options of same alternative classes with same benefits such as calcium channel blockers, Vasodilatory beta blockers etc.
Above answer was peer-reviewed by : Dr. Ashwin Bhandari
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Follow up: Dr. Prabhakar C Koregol (18 hours later)
In answer to your suggestion, unfortunately Ca. Chanel Blockers made my ankles swell and as I specified, in regard to Diovan my creatinine and Bun were high (GFR:30)

Should I continue to risk a future deterioration of my Kidneys and continue with Diovan, or try a new approach, as you suggested : Beta Blockers-- that I have never tried ?

If I put up with the dry cough caused by an Ace Inhibitor would that be a better solution than Diovan and/or Beta Blocker, in other words would my Kidneys be less injured ? Thank you for your help.
Thank you for your help.
doctor
Answered by Dr. Prabhakar C Koregol (46 minutes later)
Brief Answer:
ACE won't be option

Detailed Answer:
If you have renal function deterioration with ARB, you are likely to have same with lisinopril and hence its not option. if ccb produce swelling that is only cosmetic and no symptom you can go back on it, also there are other Ccbs such as cilidepine which cause less edema. Hence you can switch over to it.
beta blockers can also be an option.
Note: For further queries related to coronary artery disease and prevention, click here.

Above answer was peer-reviewed by : Dr. Bhagyalaxmi Nalaparaju
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Answered by
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Dr. Prabhakar C Koregol

Cardiologist, Interventional

Practicing since :1998

Answered : 427 Questions

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Suggest Treatment For Renal Dysfunction

Brief Answer: Generally no Detailed Answer: If you have experienced renal dysfunction that needed discontinuation of the drug, then all the drugs of same class should be avoided unless there is compelling indications. As there are multiple options of same alternative classes with same benefits such as calcium channel blockers, Vasodilatory beta blockers etc.