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Suggest Treatment For Itching Due To Narcotic Painkillers

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Posted on Mon, 30 Mar 2015
Question: I almost have all my questions answered in my first question. one left. I have to take narcotic painkillers because of my back & leg pain. the problem is almost all of them make me itch terribly so that the pain is as bad as the itching . I've got it narrowed down to 2 drugs that do not cause you to have "the itch". fentanyl & tramadol are synthetic opioid drugs not derived from opium and therefore do not cause the "itch". my question is no one has commented on the last drug: Demerol. Could you please on Demerol. is it still considered a safe drug and is it still prescribed? thank you.
doctor
Answered by Dr. Dr. Matt Wachsman (32 minutes later)
Brief Answer:
no, not demerol

Detailed Answer:
it's virtually off the market due to toxicity. It has all the itch (histamine release) of all of them. You are mentioning potentially one of the highest str narcotics (fentanyl) and one of the lowest (tramadol) ... they probably ARE the lowest on histamine release

but

you could take benadryl to block histamine.....
Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar
doctor
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Follow up: Dr. Dr. Matt Wachsman (21 hours later)
thank you sir for replying. Benadryl does nothing for me, it doesn't touch it. I took 4 at a time. cortisone would be the only antidote , but the doctor wasn't interested and frankly taking one drug to counteract another I do not believe is good medicine. in addition to my bulging disks, my L5 disk is almost gone. I am not interested in lyrica & Neurontin, etc., been there, done that.
I also have idiopathic edema in both legs and feet that has recently flared to the point where it resembles lymphedema and am presently at clinic with PT. on top of that I have plantar fasciitis in both feet. plus, since I stopped the injection of steroids (last one 11/18), I am long overdue, so know my dull ache is coming back in my lower back and both my legs. OTHER THAN THAT, EVERYTHING IS GREAT. so, if my doctor can give me some relief with a synthetic opioid like drug (tramadol) and it doesn't make me itch, i'll be first in line.
doctor
Answered by Dr. Dr. Matt Wachsman (2 hours later)
Brief Answer:
best of luck!

Detailed Answer:
would really have to directly examine on the edema; while it can be a sign of serious liver/kidney/heart/ or lung failure, mostly it's varicose veins or mild obesity.

tramadol besides being the lowest level of narcotic (class four), is also reasonably long lasting and reasonably safe. While one could try other anti-histamines (zyrtec), it is hard to beat just using a longer acting less potent narcotic (tramadol).

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Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar
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Answered by
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Dr. Dr. Matt Wachsman

Addiction Medicine Specialist

Practicing since :1985

Answered : 4214 Questions

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Suggest Treatment For Itching Due To Narcotic Painkillers

Brief Answer: no, not demerol Detailed Answer: it's virtually off the market due to toxicity. It has all the itch (histamine release) of all of them. You are mentioning potentially one of the highest str narcotics (fentanyl) and one of the lowest (tramadol) ... they probably ARE the lowest on histamine release but you could take benadryl to block histamine.....