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Suggest Treatment For Gastroparesis
Question: Our daughter has been diagnosed with gastroparesis. She had a procedure to insert both a J and a G tube for feeding and elimination. A CT scan recently revealed inflammation on the intestinal wall, which appears to be the cause of great pain. Blood work and an x-ray have been inconclusive. CT also showed thickening on intestinal wall; no diagnosis at present. Potassium 2 points lower causing dizziness on standing, loss of two pounds in last two day, high levels of ketones in blood.
Brief Answer:
Gastroparesis cause is unknown hence treatment is difficult.
Detailed Answer:
Hello,
Thank you for choosing HealthcareMagic for your query.
I've gone through your details and I appreciate your concern.
Firstly I am very sorry for the condition of your daughter.
Much of this problem in controlling pain originates from the fact that a complete lack of knowledge about the causes of pain in gastroparesis. Till date, there are no experimental studies or clinical trials on this subject. Therefore the approach to treatment is both arbitrary, subject to the biases of the treating physician, and empirical, without any biological rationale to guide therapy.
Neuropathic pain, pain generated by damaged or inflamed nerves, is thought to be the primary cause and is one of the most challenging types of pain to manage. Neuropathic pain is common in idiopathic. As the cause is unknown it's very difficult to treat.
The tricyclic anti-depressants drugs have become one of the mainstays for treating chronic abdominal pain in gastroparesis related inflammation.
However initial therapy with anti-inflammatory and antispasmodics like Dicyclomine and Ibuprofen can be tried. A new category of antidepressant drugs the selective serotonin and norepinephrine reuptake inhibitors (SSNRIs) are showing promise in treating neuropathic pain. Venlafaxine (Effexor) and Duloxetine (Cymbalta) are two agents being used.
Anticonvulsant anti-epileptic drugs have also demonstrated their effectiveness in clinical trials for pain associated with gastroparesis. Pregabalin and Gabapentin can be used.
Please discuss the above-mentioned possibilities with your gastroenterologist. They may be effective in case your daughter.
Again I am sorry for her problem. Frankly speaking, there is no absolute cure for this condition. Medications can be effective in controlling symptoms in some patients However results may vary from patient to patient.
The best way is to try this medication and see the results.
In case you need more details I would be glad to help.
Regards.
Gastroparesis cause is unknown hence treatment is difficult.
Detailed Answer:
Hello,
Thank you for choosing HealthcareMagic for your query.
I've gone through your details and I appreciate your concern.
Firstly I am very sorry for the condition of your daughter.
Much of this problem in controlling pain originates from the fact that a complete lack of knowledge about the causes of pain in gastroparesis. Till date, there are no experimental studies or clinical trials on this subject. Therefore the approach to treatment is both arbitrary, subject to the biases of the treating physician, and empirical, without any biological rationale to guide therapy.
Neuropathic pain, pain generated by damaged or inflamed nerves, is thought to be the primary cause and is one of the most challenging types of pain to manage. Neuropathic pain is common in idiopathic. As the cause is unknown it's very difficult to treat.
The tricyclic anti-depressants drugs have become one of the mainstays for treating chronic abdominal pain in gastroparesis related inflammation.
However initial therapy with anti-inflammatory and antispasmodics like Dicyclomine and Ibuprofen can be tried. A new category of antidepressant drugs the selective serotonin and norepinephrine reuptake inhibitors (SSNRIs) are showing promise in treating neuropathic pain. Venlafaxine (Effexor) and Duloxetine (Cymbalta) are two agents being used.
Anticonvulsant anti-epileptic drugs have also demonstrated their effectiveness in clinical trials for pain associated with gastroparesis. Pregabalin and Gabapentin can be used.
Please discuss the above-mentioned possibilities with your gastroenterologist. They may be effective in case your daughter.
Again I am sorry for her problem. Frankly speaking, there is no absolute cure for this condition. Medications can be effective in controlling symptoms in some patients However results may vary from patient to patient.
The best way is to try this medication and see the results.
In case you need more details I would be glad to help.
Regards.
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Above answer was peer-reviewed by :
Dr. Arnab Banerjee
Answered by
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