Question: Hi, I am a 33 y.o. female with a 3 years history of digestive issues. I have been previously diagnosed with IBS and gastritis. At that time I had frequent diarrhea and lower left quadrant pain.
About two years ago, I started having upper left quadrant pain and pale stools, and I did a lot of analysis including an MRI, which revealed nothing. I went gluten and lactose free and was pain-free until 2 months ago.
In july, I started having occasional dull pain on my mid right side (gallbladder location) and was feeling tiredish. The pain was worse when bending, or in positions in which my rib was hitting the spot. I went to my GP who did a serie of blood analysis and a ln abdominal ultrasound. All the findings were normal except somewhat lower ferritin (11ng/L). The US was clear. However, since the pain continued and moved also to my mid-left side under ribs and got worse after eating, or when laying down. I went to hospital for further investigation. However, all my results were normal: all blood test including pancreatic enzymes are still normal, tumor markers negative, blood sugar normal, ferritin back to normal and the contrast-enhanced CT and MRI also clear. It would all be very good if I didn't have this pain, that seems to be worse after I eat (especially if that something is fried). I feel the pain at times in my back, especially at night and NSAID don't help. I also feel that the food I eat stays undigested for a very long time. Above all, I lost 5kg (12lbs) in 3 months and I am extremely worried that I might have pancreatic cancer. I read that this cancer is somtimes quite difficult to diagnose and is often missed on CT. Please help with suggestions. Would a serious issue show up on some results? Am I crazy for suspecting that? Should I push for an EUS? What else could this be? Thank you in advance! God bless!

Hi again,

I forgot to add that I also had a colonoscopy and upper end. The only thing the doctors saw is a æn atrophy in the duodenum. They have taken a biopsy, but the results haven't returned yet.

The doctors doubt it is an organic problem, but suspect a functional problem and a milder pancreatic insuficiency. They have prescribed me digestive enzymes, and it helps me somewhat with my symptoms. In any case, just to be 100% sure it isn't something nasty, I will go through an MRCP and an EUS.

What is the probability that a CT would miss a tumor? Shouldn't the tumor be visible on CT or MRI once the symptoms start?

20% is a lot! Would a PC show abnormalities in some other results?

I try not to be paranoiac, but 20% chance is worth having an EUS done.

Thank you for your answers!