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Suggest Alternative Medication In Place Of Patch Adhesive For Skin Disease

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Posted on Wed, 23 Sep 2015
Question: What is considered the therapeutic blood level for nuvigil?
Do you have a blood level curve for single patch application of 1 mg neupro patch
for 4-8 hours?
What is considered the therapeutic blood level for rotigotine?
Do you have any suggestions for using rotigotine for a patient allergic to the patch adhesive?
Thank you,
XXXX
doctor
Answered by Dr. Dr. Erion Spaho (5 hours later)
Brief Answer:
Microemulsion rotigotine gel is an alternative to skin problems.

Detailed Answer:
Welcome back XXXXXXX

Therapeutic blood level of rotigotine is considered above 1.2 ng/ml with a Cmax of 7 ng/ml.

I don't came across any partial curve of 1 mg patch application of neupro, but, regarding to curves, the level approximately after 6 hours should be around 1 ng/ml.

As far as I know, there is developed microemulsion-based rotigotine gel with significant lower skin irritation effects, a good alternative to use by patients that experienced serious skin problems.

I didn't find any information about blood therapeutic levels of nuvigil, oral doses ranges between 50 to 400 mg/day.

Hope I helped.

Take care.
Above answer was peer-reviewed by : Dr. Raju A.T
doctor
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Follow up: Dr. Dr. Erion Spaho (3 hours later)
Thank you very much--you have been extremely helpful.
And I will certainly return to you if or when I have other questions.
XXXX
doctor
Answered by Dr. Dr. Erion Spaho (35 minutes later)
Brief Answer:
You are welcome.

Detailed Answer:
Glad I helped you XXXXXXX Thanks for the kind words.

Best regards.
Note: For further follow up on related General & Family Physician Click here.

Above answer was peer-reviewed by : Dr. Yogesh D
doctor
Answered by
Dr.
Dr. Dr. Erion Spaho

Neurologist, Surgical

Practicing since :2004

Answered : 4493 Questions

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Suggest Alternative Medication In Place Of Patch Adhesive For Skin Disease

Brief Answer: Microemulsion rotigotine gel is an alternative to skin problems. Detailed Answer: Welcome back XXXXXXX Therapeutic blood level of rotigotine is considered above 1.2 ng/ml with a Cmax of 7 ng/ml. I don't came across any partial curve of 1 mg patch application of neupro, but, regarding to curves, the level approximately after 6 hours should be around 1 ng/ml. As far as I know, there is developed microemulsion-based rotigotine gel with significant lower skin irritation effects, a good alternative to use by patients that experienced serious skin problems. I didn't find any information about blood therapeutic levels of nuvigil, oral doses ranges between 50 to 400 mg/day. Hope I helped. Take care.