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Is Demyelinating Polyneuropathy Curable?

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Posted on Tue, 9 May 2023
Question: Ms XXXXXXX is having histoyr of demylinating polyradiculopathy. complain of Numbness & Tingling was started in XXXXXXX 2017 & she was diagnosed with said disease after 1 month.after diagnosis she was hospitalization for 10 days & treated. request you to help us to understand following
1.is this disease curable ?
2. how much time it will take/ what is prognosis of disease ?
3. is it recurrent in nature ?- what are chances & how can we avoid it

doctor
Answered by Dr. Ishu Bishnoi (8 hours later)
Brief Answer:
Answer of your questions

Detailed Answer:

Hi,

(1) Demyelinating polyneuropathy is curable if it is due to vitamin B12 deficiency, G B syndrome, following viral infection. But if it is due to autoimmune disorder, paraneoplastic syndrome due to malignancy and chronic (passed curable time), then it is not curable but controlled. NCV and nerve biopsy help in confirming the type of damage.

(2) Usually curable neuropathy starts responding within a week and patients recover in a month's time. Some sensory symptoms like tingling may persist for longer duration.

(3) If it is due to G B syndrome (Gullian-Barre syndrome), it will not recur. B12 deficiency can happen again. It can be avoided by taking diet high in B12 (curd, meat, eggs, milk) and B12 capsules (methylcobalamine 1500 microgram). While autoimmune disease can only be suppressed by medication. It usually recur whenever medicines are discontinued.

Hope it will help you. If you have any doubt, do let me know.
Thanks. Take care.

Regards,
Dr. Ishu Bishnoi
Neurologist, Surgical
Above answer was peer-reviewed by : Dr. Prasad
doctor
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Follow up: Dr. Ishu Bishnoi (2 days later)
Thank YOu Doctor for provided.
could you help us to understand causes & prognosis of Ms XXXXXXX with help of attached medical documents.
doctor
Answered by Dr. Ishu Bishnoi (7 hours later)
Brief Answer:
Reports interpretation

Detailed Answer:

Hi,

First two reports are suggesting:

- The patient is suffering from autoimmune demyelinating polyneuropathy. The causative disorder is not mentioned. However, ANA is positive, which means it can be lupus erthymatosis associated neuropathy.

Prognosis of autoimmune neuropathy - It can be controlled by immunosuppressants like steroid and chemotherapy. She is already receiving Prednisone (steroid) for it. As soon as her autoimmunity will be controlled, her nerves will recover. However, the neuropathy usually shows recurrent remissions.

Second two reports:

They are about molluscum contageosum, which is a type of virus. It can form skin warts. It can be completely treated by medication and lesions can be cauterised or excised.

Hope it will help you. Thanks. Take care.

Regards,
Dr. Ishu Bishnoi
Neurologist, Surgical
Above answer was peer-reviewed by : Dr. Prasad
doctor
Answered by
Dr.
Dr. Ishu Bishnoi

Neurologist, Surgical

Practicing since :2007

Answered : 901 Questions

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Is Demyelinating Polyneuropathy Curable?

Brief Answer: Answer of your questions Detailed Answer: Hi, (1) Demyelinating polyneuropathy is curable if it is due to vitamin B12 deficiency, G B syndrome, following viral infection. But if it is due to autoimmune disorder, paraneoplastic syndrome due to malignancy and chronic (passed curable time), then it is not curable but controlled. NCV and nerve biopsy help in confirming the type of damage. (2) Usually curable neuropathy starts responding within a week and patients recover in a month's time. Some sensory symptoms like tingling may persist for longer duration. (3) If it is due to G B syndrome (Gullian-Barre syndrome), it will not recur. B12 deficiency can happen again. It can be avoided by taking diet high in B12 (curd, meat, eggs, milk) and B12 capsules (methylcobalamine 1500 microgram). While autoimmune disease can only be suppressed by medication. It usually recur whenever medicines are discontinued. Hope it will help you. If you have any doubt, do let me know. Thanks. Take care. Regards, Dr. Ishu Bishnoi Neurologist, Surgical