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Is Vraylar Medication Effective At Treating Alogia And Anhedonia?

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Posted on Sat, 4 Nov 2017
Question: I I am the person who asked about vraylar new medication.when u say maximum effect for this drug on alogia amotivation anhedomia? In % how much the improvement?
doctor
Answered by Dr. Dr. Ashok Kumar Choudhary (5 hours later)
Brief Answer:
More than one third improvement in these negative symptoms

Detailed Answer:
Hello,
Thanks for follow up.


As stated earlier we do not have adequate data for individual negative symptoms of schizophrenia however the available studies show that you can expect average 30% more improvement in negative symptoms and cognitive symptoms.

Considering the fact that there is better improvement in certain negative symptoms it can be stated that there is around 40% improvement for anhedonia, amotivation and alogia.

I need to emphasize here that other symptoms may not respond alike the amotivation, alogia and anhedonia and the improvement may be limited in affective flattening.

I hope this clarifies.
Feel free to write back to me if you have more questions.
Thanks and regards.
Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar
doctor
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Follow up: Dr. Dr. Ashok Kumar Choudhary (24 minutes later)
abilify do i take how much is the improvement on negative symptoms? u have an idea dr
doctor
Answered by Dr. Dr. Ashok Kumar Choudhary (8 hours later)
Brief Answer:
Around one third to two third of Cariprazine

Detailed Answer:
Hello,
Thanks for reverting back to me.

Alike cariprazine, abilify is also partial dopamine agonist and have some effect on negative symptoms. Roughly speaking the negative symptoms get improved by 10-20 % with Abilify. In another words the effect on negative symptoms with abilify can be one third to two third of cariprazine.

I hope this answers you.
Write back to me if you have more questions.
Thanks again.
Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar
doctor
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Follow up: Dr. Dr. Ashok Kumar Choudhary (52 minutes later)
finaly question i can say %improvement for negative symptoms = % reduce for negative symptoms.or not? i can concluse that person on new medication vraylar became 40 percent normale on negative symptoms? and thx dr
doctor
Answered by Dr. Dr. Ashok Kumar Choudhary (36 minutes later)
Brief Answer:
Yes

Detailed Answer:
Hello,
Thanks for follow up.

My answer is yes. We can expect overall 40% improvement in negative symptoms. However I like to acknowledge that individual variation do occur and not everyone responds equally. It is possible that you may have better improvement than what is known as per the studies and vise versa.

Thanks again.
Note: For further follow up on related General & Family Physician Click here.

Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar
doctor
Answered by
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Dr. Dr. Ashok Kumar Choudhary

Psychiatrist

Practicing since :2000

Answered : 3355 Questions

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Is Vraylar Medication Effective At Treating Alogia And Anhedonia?

Brief Answer: More than one third improvement in these negative symptoms Detailed Answer: Hello, Thanks for follow up. As stated earlier we do not have adequate data for individual negative symptoms of schizophrenia however the available studies show that you can expect average 30% more improvement in negative symptoms and cognitive symptoms. Considering the fact that there is better improvement in certain negative symptoms it can be stated that there is around 40% improvement for anhedonia, amotivation and alogia. I need to emphasize here that other symptoms may not respond alike the amotivation, alogia and anhedonia and the improvement may be limited in affective flattening. I hope this clarifies. Feel free to write back to me if you have more questions. Thanks and regards.