Question: I recently noticed that i have been unconsciously rolling my left thumb and forefinger together in a circular pattern. I know from classes I took in neurology that it is called "pin-rolling." I have been doing it for more than a year but I am doing it more often now.

I know it is a sign of Parkinson's disease (which my father has) but I'm wondering if it could be related to the medications I take (Lamictal, celexa, trazodone, low dose klonopin...occasionally ritalin or modafinil). When I take celexa I frequently wake up with significant tremors, and racing, fractured, uncomfortable thoughts. A small amount of coffee or tea calms them and I can sometimes return to sleep.

Thank you. I only take 100mg of brand name lamictal. But I have taken it since 2005 at varying doses. Higher doses result in sleep and cognitive disturbances, headaches.

I have also been taking klonopin .25-.5 mgs daily since 2011. I have had numerous brief trials with gabapentin, trileptal, several second generation neuroleptics over the years, and most recently almost two years on MAOIs (which is when I noticed it first). I have also been on anti-HIV drugs since 2005.

My father has also been taking psych meds most of his life and believes seizure-like activity began after years of taking lamictal also. Mine mostly occur before-during sleep or at waking. Sleep neurologist found nothing.

I THINK I only do this on my left side, where I've had various parasthesias over the years. I also have cervical nerve impingement on the left side.

Unfortunately, Lamictal is one of the only consistently helpful parts of my medication regimen.

Is there a way to test for this without stopping lamictal and/or rule out other issues? An MRI?

Thank you