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How Reliable Is The Modern 3rd Generation Antibody Test?

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Posted on Mon, 29 Dec 2014
Question: After 18 weeks of sexual exposure with one commercial sex worker I had HIV test. Result was negative.
It was 3rd Generation antibody test. Test method was Enhanced chemiluminescence.
Is it a modern 3rd generation Antibody Test?
Is this result final?
Shall I need any further test?
doctor
Answered by Dr. Sankaranantham Murugan (22 minutes later)
Brief Answer:
Highly reliable and you are almost HIV free

Detailed Answer:
Hi,
Welcome to HCM.
Thanks for posting your query.

HIV test after 18 weeks is very much conclusive. 3rd Generation Chemiluminescence test is very much specific and reliable. So a nonreactive HIV Chemiluminescence test assures you that you are free from HIV to an extent of 99%. If one more negative HIV test would increase the sensitivity to 100%.
Dr S.Murugan
Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar
doctor
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Follow up: Dr. Sankaranantham Murugan (4 minutes later)
Thanks for your answer.
Many doctors in this site claiming 6 months test is conclusive.
Very much contradicting with each other.
One doctor said to me that since 2004 HIV antibody test window period changed from 6 months to 3 months.
On whom to believe? I am in extreme stress. Is my test a Modern HIV antibody test?
doctor
Answered by Dr. Sankaranantham Murugan (14 minutes later)
Brief Answer:
Window period extend in persons who are on immunosuppressive drugs

Detailed Answer:
Hi,
Welcome back.

In normal conditions for a normal person, window period does not exceed 12 weeks in my experience in HIV field of past 25 years. Only in people who are on steroids, other immune suppressive drugs and cyto-toxic drugs and those who had taken irregular PEP (ART drugs), the window period can get extended up to 6 months.
So your test is very much conclusive Nothing to worry.
Dr S.Murugan
Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar
doctor
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Follow up: Dr. Sankaranantham Murugan (1 minute later)
Is my test a Modern HIV antibody test?

Also my last exposure was Deep tongue kissing.
doctor
Answered by Dr. Sankaranantham Murugan (4 minutes later)
Brief Answer:
Chemiliminescence HIV test is advanced technique, ruled out HIV

Detailed Answer:
HI,
Welcome once again.
Never mind about deep kissing etc. Your test is very much advanced one. So the non-reactive test assured that you are HIV free.
Dr S.Murugan
Note: Consult a Sexual Diseases Specialist online for further follow up- Click here.

Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar
doctor
Answered by
Dr.
Dr. Sankaranantham Murugan

HIV AIDS Specialist

Practicing since :1974

Answered : 3110 Questions

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How Reliable Is The Modern 3rd Generation Antibody Test?

Brief Answer: Highly reliable and you are almost HIV free Detailed Answer: Hi, Welcome to HCM. Thanks for posting your query. HIV test after 18 weeks is very much conclusive. 3rd Generation Chemiluminescence test is very much specific and reliable. So a nonreactive HIV Chemiluminescence test assures you that you are free from HIV to an extent of 99%. If one more negative HIV test would increase the sensitivity to 100%. Dr S.Murugan