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How Reliable Is P24 Antigen Test For HIV After 15 Days Of Possible Sexual Exposure?

Posted on Tue, 26 May 2015

Question: Hi Doc, I would like to konw how reliable the p24 test is after 15 days.
Thanks

Answered by Dr. Sankaranantham Murugan (1 hour later)

Brief Answer:
P24 Antigen test is conclusive by 4 weeks after high risk contact.

Detailed Answer:
Hi,
Welcome to HCM.
Thanks for posting your query.

P24 Antigen detects the the HIV 1 infection as early as 7 days on wards following an infection. But this can be considered more conclusive 4 weeks after the high risk contact to either confirm or rule out HIV 1 infection.
Dr S.Murugan

Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar

Follow up: Dr. Sankaranantham Murugan (4 hours later)

Hi Doc, how reilable the p24 ag and 4th gen combo ab test combine test is.

Thanks

Answered by Dr. Sankaranantham Murugan (2 hours later)

Brief Answer:
both are highly reliable tests

Detailed Answer:
Hi,
Welcome back.
Both tests are highly reliable. Both will rule out or confirm HIV 1 infection by 4 weeks after the high risk contact. 4th generation COMBO test will be 100% conclusive for both HIV 1and 2 infections by the completion of 12 weeks.
Dr S Murugan

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Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar