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How Long Does Alzheimer's Disease Take To Progress From Initial Stage To The Last Stage?

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Posted on Wed, 7 May 2014
Question: My father-in-law was diagnosed 2-3 yrs. ago with early onset Alzheimer's Disease. My husband and I moved in with him one year ago. He is 88 yrs. old and his lovely bride died about 6 yrs. ago. Hospice now comes in to provide different services. Within past week, several changes occurred: increased agitation, boundless appetite (eating approx. 20 times a day) and repetetive behaviors. He carries diagnoses of CHF, kidney problems and need for oxygen 24/7 which he keeps on half the time. Another big change..weakness (dropping and breaking things, spilling things over. He's no longer allowed outside walks unless in wheelchair. Hospice says he's end stage of disease and focus is to make him comfortable with morphine q 4 hrs. and Haldol q 6 hrs. We were told this phase is temporary and eventually he won't remember anything. I've retrieved CDs of Big Band music which he enjoyed dancing to and singing with his late wife. He and I have enjoyed listening to, dancing and singing along for several years. He enoys also looking at family photos and houses he built for his family past 60 yrs. Question.....is there a rough estimate of time from when he reaches last stage Alzheimer's to where he has totally forgotten recent past and who we are? Currently he can feed, shower, shave and use bathroom without assist. My 2 step-daughters are coming tomorrow night to see their grandfather as they learned today the sudden and drastic shit in him. what do we say, what is an average time frame from now till he forgets everything (blessing and calm in a way,
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Answered by Dr. Anjana Rao Kavoor (6 hours later)
Brief Answer: 5-10 years Detailed Answer: Hi, Thanks for writing to us, I went through the history provided by you. Early-onset Alzheimer's Disease is diagnosed if the disease begins before the age of 65 years. You say that he was diagnosed 3 years ago, can you specify at what age did his symptoms begin? What are the memory problems he is facing right now(before the acute change in his behavior from one week)? Does he have difficulty naming or finding words at times? Does he forget names of newly introduced people? Does he misplace objects at home? Does he have difficulty in remembering new facts? These are the usual symptoms of early stage which later progress to- inability to carry out day to day activities and inability to recognize and socially inappropriate symptoms. Alzheimers disease is a slowly progressive disease. The progression from early stage to late stage takes 5 to 10 years in most patients. The stages may also overlap in some patients. The symptoms of agitation and repetitive behaviors may be psychosis which is seen in 40-50% of the patients during the course of the illness. Haloperidol is an antipsychotic that is used to treat the condition. Psychosis usually resolves with treatment. Hope this helps Dr A Rao
Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar
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Answered by
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Dr. Anjana Rao Kavoor

Psychiatrist

Practicing since :2008

Answered : 1197 Questions

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How Long Does Alzheimer's Disease Take To Progress From Initial Stage To The Last Stage?

Brief Answer: 5-10 years Detailed Answer: Hi, Thanks for writing to us, I went through the history provided by you. Early-onset Alzheimer's Disease is diagnosed if the disease begins before the age of 65 years. You say that he was diagnosed 3 years ago, can you specify at what age did his symptoms begin? What are the memory problems he is facing right now(before the acute change in his behavior from one week)? Does he have difficulty naming or finding words at times? Does he forget names of newly introduced people? Does he misplace objects at home? Does he have difficulty in remembering new facts? These are the usual symptoms of early stage which later progress to- inability to carry out day to day activities and inability to recognize and socially inappropriate symptoms. Alzheimers disease is a slowly progressive disease. The progression from early stage to late stage takes 5 to 10 years in most patients. The stages may also overlap in some patients. The symptoms of agitation and repetitive behaviors may be psychosis which is seen in 40-50% of the patients during the course of the illness. Haloperidol is an antipsychotic that is used to treat the condition. Psychosis usually resolves with treatment. Hope this helps Dr A Rao