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Hello, If My Results From A SERUM PROTEIN ELECTROPHORESIS Test

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Posted on Wed, 5 Aug 2020
Question: Hello,

If my results from a SERUM PROTEIN ELECTROPHORESIS test are normal, do I still have the chance of being diagnosed with multiple mieloma or similar cancers? Than you
doctor
Answered by Dr. Shailja Puri (2 hours later)
Brief Answer:
Normal protein electrophoresis rules out multiple myeloma

Detailed Answer:
Hello,
Thanks for posting your query on Ask A Doctor forum.
Serum protein electrophoresis is one of the most important and diagnostic investigation for multiple myeloma.
A normal serum electrophoresis rules out multiple myeloma.
However, clinical features, albumin: globulin ratio, haemoglobin levels, ESR are some of the investigations which will help in the diagnosis.
There are other plasma cell dyscrasias also besides multiple myeloma which are milder than multiple myeloma.
I suggest you to upload the laboratory reports which have been done for interpretation.

Thanks and take care
Dr Shailja Puri

Above answer was peer-reviewed by : Dr. Nagamani Ng
doctor
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Follow up: Dr. Shailja Puri (2 days later)
Hello Dr.

Than you for your response.

The following tests came back normal:

Free Kappa/Lambda
Immunofix-urine
Serum proteine electro
Hemoglobin Eval
Folate
Methimalo. Acid

However, I have been referred to a hematologyst/onco. Have an idea of what is going on with my blood? Thank you very much.
doctor
Answered by Dr. Shailja Puri (4 minutes later)
Brief Answer:
Investigations rule out possibility of plasma cell dyscrasia

Detailed Answer:
Hello and welcome again,
The investigations - serum electrophoresis, urine electrophoresis and kappa/ lambda chain within normal rage rule out possibility of plasma cell dyscrasia.
Referral to hematologist is probably due to low hemoglobin as mentioned by you in your post.

Thanks and take care
Dr Shailja Puri




Above answer was peer-reviewed by : Dr. Prasad
doctor
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Follow up: Dr. Shailja Puri (31 minutes later)
Thank you again, Dr. Puri.

Do you know what the remaining options are? Thank you.

All the best,
Enric
doctor
Answered by Dr. Shailja Puri (14 hours later)
Brief Answer:
Cause of low hemoglobin needs to be found out

Detailed Answer:
hello and welcome again,
Low hemoglobin at your age can occur due to various causes.
Firstly, iron deficiency has to be ruled out by getting a peripheral blood smear examination, serum iron levels and ferritin levels done.

In case iron deficiency is detected, iron supplements have to be taken to correct the deficiency and the cause of iron deficiency has also to be found out.

Thanks and take care
Dr Shailja Puri
Note: Do you have more questions on diagnosis or treatment of blood disorders? Ask An Expert/ Specialist Now

Above answer was peer-reviewed by : Dr. Kampana
doctor
Answered by
Dr.
Dr. Shailja Puri

Pathologist and Microbiologist

Practicing since :2006

Answered : 9705 Questions

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Hello, If My Results From A SERUM PROTEIN ELECTROPHORESIS Test

Brief Answer: Normal protein electrophoresis rules out multiple myeloma Detailed Answer: Hello, Thanks for posting your query on Ask A Doctor forum. Serum protein electrophoresis is one of the most important and diagnostic investigation for multiple myeloma. A normal serum electrophoresis rules out multiple myeloma. However, clinical features, albumin: globulin ratio, haemoglobin levels, ESR are some of the investigations which will help in the diagnosis. There are other plasma cell dyscrasias also besides multiple myeloma which are milder than multiple myeloma. I suggest you to upload the laboratory reports which have been done for interpretation. Thanks and take care Dr Shailja Puri