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Hello I Hope This Qestion Will Go To Infectalogist! As

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Posted on Thu, 23 Jun 2022
Question: Hello
I hope this qestion will go to infectalogist!

As i travel to XXXXXXX and have risk of Schistosomiasis

The qestion how much % of acute Schistosomiasis develop Katayama syndrome ?
Katayama syndrome mortality is 25 %

Schistosomiasis is important to diagnose and treat early !

So if i have trevel to risk country and still have no symptoms - it is better to diagnose Schistosomiasis so i can avoid chronic complications !
Am i right ?

Thank you very much
doctor
Answered by Dr. salah saad shoman (46 minutes later)
Brief Answer:
Often

Detailed Answer:
Dear sir, I have gone through your question and I understand your concerns but katayama syndrome is the acute schistosomiasis and can occur often in early stages of infection.. However I would recommend that you take prophylactic Praziquantel treatment post exposure; a single dose of 40 mg per kg.. I hope you find this helpful
Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar
doctor
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Follow up: Dr. salah saad shoman (11 days later)
Thank you very much !

As reading too much can make you stress as you dont undestand lot of things - and you misunderstand them !

What is mortality of Katayama syndrome ?

As in some literature it is said

Acute schistosomiasis is associated with a mortality rate of up to 25% in some series.

https://emedicine.medscape.com/article/228392-overview#a7


Acute Schistosomiasis, or Katayama fever,36 can increase the mortality rate by up to 25%

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC0000/

It is no said - is it mortality with treatment or with no treatment !

In literature about Katayama syndrome - it is said

; patients respond well to regimens of praziquantel with
and without steroids.

https://sci-hub.se/10.1016/S1473-3099(07)70053-1

Persons with positive fecal and/or serologic specimens were treated with a single oral dose of praziquantel (40 mg/kg). All symptoms resolved after treatment, and no serious adverse reactions to therapy were reported.

https://www.cdc.gov/mmwr/preview/mmwrhtml/0000.htm

Although schistosomiasis is rarely fatal, it causes long-term morbidity such as anaemia and other complications as mentioned above.

https://patient.info/doctor/schistosomiasis-pro

So how it is - Katayama syndrome with appropriate treatment mortality is low ?

And it could be as 25 % high if there is no treatment ?

Than you very much !
doctor
Answered by Dr. salah saad shoman (18 hours later)
Brief Answer:
Mortality rate with no treatment

Detailed Answer:
Dear sir, I have gone through your question and understand your concerns but since developing symptoms can take time post infection to develop and this might lead to a late diagnosis of schistosomiasis.. I would recommend a prophylactic dose of praziquantel post exposure to a possible infection.
Mortality rate is associated with no treatment or late diagnosis..
Steroids are added to relieve symptoms of schistosomiasis and not as a cure..
Note: Get personalized answers to your HIV related queries You can choose to talk face to face with your doctor. Book a Video Call now.

Above answer was peer-reviewed by : Dr. Vaishalee Punj
doctor
Answered by
Dr.
Dr. salah saad shoman

Internal Medicine Specialist

Practicing since :2004

Answered : 3153 Questions

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Hello I Hope This Qestion Will Go To Infectalogist! As

Brief Answer: Often Detailed Answer: Dear sir, I have gone through your question and I understand your concerns but katayama syndrome is the acute schistosomiasis and can occur often in early stages of infection.. However I would recommend that you take prophylactic Praziquantel treatment post exposure; a single dose of 40 mg per kg.. I hope you find this helpful