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Question: Hello - i know that you are endorinalogist - and you gone understand this article
i have question about your article
The treatment outcomes were further classified as successful (cured and completed treatment), or unsuccessful (died, failed treatment, loss to follow up, changed diagnosis, ongoing treatment and treatment interrupted).
In multivariable analysis, a TB patient with DM has 3.5 higher odds to develop unsuccessful treatment outcome compared to TB patients without DM
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC0000/#!po=45.3125
I studied it - about diabetes and TB treatment outcome - if i look on table 4
I did not find any huge difference less number with Diabetes completed treatment, and failed treatment more diabetes group
But looking one other numbers - diabetes had fewer %
If in article said
In multivariable analysis, a TB patient with DM has 3.5 higher odds to develop unsuccessful treatment outcome compared to TB patients without DM
How can you get such mummer difference that DM have less successful treatment outcome ? -
i can not understand
Please can you give me small comment
Thank you very much
i have question about your article
The treatment outcomes were further classified as successful (cured and completed treatment), or unsuccessful (died, failed treatment, loss to follow up, changed diagnosis, ongoing treatment and treatment interrupted).
In multivariable analysis, a TB patient with DM has 3.5 higher odds to develop unsuccessful treatment outcome compared to TB patients without DM
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC0000/#!po=45.3125
I studied it - about diabetes and TB treatment outcome - if i look on table 4
I did not find any huge difference less number with Diabetes completed treatment, and failed treatment more diabetes group
But looking one other numbers - diabetes had fewer %
If in article said
In multivariable analysis, a TB patient with DM has 3.5 higher odds to develop unsuccessful treatment outcome compared to TB patients without DM
How can you get such mummer difference that DM have less successful treatment outcome ? -
i can not understand
Please can you give me small comment
Thank you very much
Brief Answer:
Blood sugar controll
Detailed Answer:
Hi,
Thanks for your query.
Its not just being diabetic matters here. Its the blood sugar control. Patients with good glycemic control can have successful treatment and ones which poor control can end up with unsuccessful treatment or relapse in the future.
The treatment course remains the same in diabetic and non diabetic. Its the glycemia which determines the outcome.
If in long-term diabetic which micro/ macrovascular complications already set in, the success of TB treatment matters on which end-organ damage is established. The clearance of medications, contraindications, toxicities etc an be one of the causes of treatment failure if the organs involved are damaged due to diabetes no matter the glycemic control.
Hope, I answered your query.
Please do ask if any doubts
Regards,
Blood sugar controll
Detailed Answer:
Hi,
Thanks for your query.
Its not just being diabetic matters here. Its the blood sugar control. Patients with good glycemic control can have successful treatment and ones which poor control can end up with unsuccessful treatment or relapse in the future.
The treatment course remains the same in diabetic and non diabetic. Its the glycemia which determines the outcome.
If in long-term diabetic which micro/ macrovascular complications already set in, the success of TB treatment matters on which end-organ damage is established. The clearance of medications, contraindications, toxicities etc an be one of the causes of treatment failure if the organs involved are damaged due to diabetes no matter the glycemic control.
Hope, I answered your query.
Please do ask if any doubts
Regards,
Above answer was peer-reviewed by :
Dr. Chakravarthy Mazumdar
Answered by
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