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Does Vitamin B5 Help In Treating High Cholesterol Levels?

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Posted on Fri, 24 Jun 2016
Question: I recently read that vitamin B5 may be helpful against cholesterol and would like to know if that's true. Thank you.
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Answered by Dr. Ilir Sharka (33 minutes later)
Brief Answer:
I would explain as follows:

Detailed Answer:
Hello!

Welcome back on HCM!

Regarding your concern, I would explain that the information you have provided on Vitamin B5 is right.

Vitamin B5 (pantothenic acid) and its derivatives has been shown to exert an obvious hypolipemiant effect.

Vitamin B5 (pantothenic acid) leads to the naturally synthesized compound within our bodies, called Panthetine, which in conjunction with intermediary cysteamine inhibits two enzymes acetyl coenzyme (CoA) carbocylase and HMG-CoA (3-hydroxy-3-methyl-glutaryl-CoA) reductase, thereby inhibiting triglycerides and cholesterol synthesis.

It has been shown by several studies that Vitamin B5 decreases serum total cholesterol, triglycerides, LDL-C, apolipoprotein (Apo) A-I, and Apo-B.

So, the definite answer is: Yes!

But, before deciding to use it, I recommend you discussing with your attending physician on the most appropriate therapeutic regimen (dose titration and potential side effects monitoring).

Hope you will find this answer of some help.

In case of any further uncertainties, feel free to ask me again.

Kind regards,

Dr. Iliri
Note: For further queries related to coronary artery disease and prevention, click here.

Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar
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Answered by
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Dr. Ilir Sharka

Cardiologist

Practicing since :2001

Answered : 9536 Questions

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Does Vitamin B5 Help In Treating High Cholesterol Levels?

Brief Answer: I would explain as follows: Detailed Answer: Hello! Welcome back on HCM! Regarding your concern, I would explain that the information you have provided on Vitamin B5 is right. Vitamin B5 (pantothenic acid) and its derivatives has been shown to exert an obvious hypolipemiant effect. Vitamin B5 (pantothenic acid) leads to the naturally synthesized compound within our bodies, called Panthetine, which in conjunction with intermediary cysteamine inhibits two enzymes acetyl coenzyme (CoA) carbocylase and HMG-CoA (3-hydroxy-3-methyl-glutaryl-CoA) reductase, thereby inhibiting triglycerides and cholesterol synthesis. It has been shown by several studies that Vitamin B5 decreases serum total cholesterol, triglycerides, LDL-C, apolipoprotein (Apo) A-I, and Apo-B. So, the definite answer is: Yes! But, before deciding to use it, I recommend you discussing with your attending physician on the most appropriate therapeutic regimen (dose titration and potential side effects monitoring). Hope you will find this answer of some help. In case of any further uncertainties, feel free to ask me again. Kind regards, Dr. Iliri