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Does taking marijuana with Xeralto cause bleeding?

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Infectious Diseases Specialist
Practicing since : 1973
Answered : 545 Questions
I take Xeralto each day to prevent a recurrence of four pulmonary emboli two years ago. I also have an autoimmune disease (Reiters Syndrome, also called reactive arthritis) for which I am taking a lot of pain medications. I am carefully monitored by a top blood doctor and a top pain doctor every month. We have been discussing the ability to lower my pain medication by substituting small quantities of medical marijuana. I tried a little this week for the first time in my life, cut my pain meds in half, and felt better than I have felt in years. However, I am concerned that taking marijuana with Xeralto, could cause bleeding. I have not been able to reach my blood doctor. What do you think?
Posted Fri, 17 Jan 2014 in Medicines and Side Effects
Answered by Dr. Fatbardha Sejdini 1 hour later
Brief Answer: Please keep following with your top blood doctor.. Detailed Answer: Hi, I understand your concern and it is true that marijuana can increase the risk of bleeding. On the other hand, such risk is doubled when using Xarelto. However, if your doctor was the one who prescribed them together, then I would go ahead and follow his/her advise. The doctor should be able to monitor the progress as well as risk of bleeding with help of regular blood test and guide you accordingly. Please bare in mind to keep following up with the top blood doctor and run regular blood tests to check for bleeding. All the best! Dr.Bardha Feel free to ask me other questions you might have
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Follow-up: Does taking marijuana with Xeralto cause bleeding? 4 hours later
Thank you for your advice. I will get hold of my blood doctor. Most of what I had found on the internet indicated that Marijuana was not a blood thinner, so I tried a very little in vapor, and got an immediate good result. Unfortunately, I will have to bridge the pain doctor with the blood doctor. The pain doctor prescribed the pain medication and we only talked in passing about marijuana--I gave him the research I had found concerning it's positive action with Reiter's. Then I tried a little because I figured it wasn't worth doing all the work if it didn't help. It was tremendous on both inflammation reduction and pain-relief. I could possibly cut out 2/3rds of the XXXXXXX narcotics I take now. However, Xarelto is very new here and I am sure he was not thinking about that when we talked. He was just sort of amazed I had survived four bilateral emboli--infarcted. And I did not mention the marijuana to the blood doctor, again, because I did not believe it could have that much of an impact that it was worth trying. My kids saw me suffering, even with all the drugs, and begged me to try it a few days ago. I tried it in vapor, but the Reiter's causes COPD so it is not good for my lungs--I think. I wanted to try it in an edible form, and that's when I looked it up because that is a more long lasting proposition. May I ask one thing? Where did you get the information that bleeding was doubled with marijuana and Xarelto? I can understand the issue with Cummadin, which I failed on--but Xarelto thins by a completely different mechanism. Thanks for your kind response. Henry
Answered by Dr. Fatbardha Sejdini 11 hours later
Brief Answer: Please follow the suggestions below... Detailed Answer: Hi again XXXXXXX Thank you for providing more of your medical data. Xarelto is a new drug for blood clotting. Marijuana increases the risks for bleeding. So, it is necessary to do some dose adjustment of Xarelto by your blood doctor if your pain doctor advised to start using Marijuana. However, I strongly advise to consult both doctors to prevent complications, especially those with bleeding. Marijuana is still an opioid. Apart causing COPD, it will also cause dependence. Coumadin (Warfarin) antagonize vitamin K while Xarelto inhibits the Factor Xa in the cascade of the coagulation. You can further your reading: WWW.WWWW.WW Both of them prevent blood clotting with the potential risk of bleeding. That's why I strongly advise my patients who are taking blood-thinning drugs to look for bleeding as the most common complication. Once again, I strongly advise to keep following with blood and pain doctors at the same time and give them all the medical data (complains, drugs you take,etc.) to them for better assistance and guide. All the best! Hope your pain will come to an end this New-up-coming-Year! Dr.Bardha
Above answer was peer-reviewed by
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