Brief Answer: Please refer to the answer below. Detailed Answer: Hi, I read your query and understood your concern. No, the medication can not cause venous insufficiency, but they can exacerbate it. The venous insufficiency in your case is most probably due to: - Overweight/obesity. - Lack of physical activity. - Hypertension - Heart failure If i was your treating doctor I would recommend: - Raise your legs up more than three times a day - Reduce your weight - Reduce sodium intake - Increase your physical activity. Also using Hydralazine may relief the symptoms especially the edema but should be used with care (hypotension may occur). Hope i answered to your query. Dr. Benard Shehu

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