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Does Diphenhydramine HCL Have Any Effect On The Kidneys?

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Posted on Mon, 30 Jan 2017
Question: Does diphenhydramine HCL have any effect on kidneys?

THE REASON I ASK IS BECAUSE I HAVE A CREATININE LEVEL WHICH IS JUST AT THE TOP OF THE REASONABLE RANGE (1.5) AND I TAKE THE DIPHEN... AS A SLEEP AID. I HAVE STOPPED TAKING NSAIDS OR IBUPROFEN BECAUSE OF THE EFFECT ON THE KIDNEYS. I HAVE ALSO INCREASED MY HYDRATION. ANY OTHER WAYS TO GET THE CREATININE LEVEL DOWN?
doctor
Answered by Dr. Ravi Bansal (29 hours later)
Brief Answer:
diphenhydramine is safe

Detailed Answer:

Hi,

if you have a serum creatinine of 1.5 it shows that you have early kidney damage. As per information provided by you pain killers are a common cause of renal damage and you have rightly stopped them . for pain you should take paracetamol or tramadol.

diphenhydramine HCL is safe for renal patients is has no renal toxicity

other ways to decrease your creatinine-

1. critical analysis of all your medicines by your doctor to see if any nephrotoxic effect is there from any medicine.

also your treating doctor can identify any acute disease factor contributing to rise in serum creatinine.

2. better BP control 130/80 or less under guidance of your doctor.

3. cut down on meat intake - 0.8 gm/kg / day protein intake. So try to avoid meat products .

there is other way to reduce serum creatinine.

best wishes.

in case of any further query please right-in.

Note: For further queries related to kidney problems and comprehensive renal care, talk to a Nephrologist. Click here to Book a Consultation.

Above answer was peer-reviewed by : Dr. Nagamani Ng
doctor
Answered by
Dr.
Dr. Ravi Bansal

Nephrologist

Practicing since :1996

Answered : 359 Questions

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Does Diphenhydramine HCL Have Any Effect On The Kidneys?

Brief Answer: diphenhydramine is safe Detailed Answer: Hi, if you have a serum creatinine of 1.5 it shows that you have early kidney damage. As per information provided by you pain killers are a common cause of renal damage and you have rightly stopped them . for pain you should take paracetamol or tramadol. diphenhydramine HCL is safe for renal patients is has no renal toxicity other ways to decrease your creatinine- 1. critical analysis of all your medicines by your doctor to see if any nephrotoxic effect is there from any medicine. also your treating doctor can identify any acute disease factor contributing to rise in serum creatinine. 2. better BP control 130/80 or less under guidance of your doctor. 3. cut down on meat intake - 0.8 gm/kg / day protein intake. So try to avoid meat products . there is other way to reduce serum creatinine. best wishes. in case of any further query please right-in.