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Diabetic, Taking Novolog & Glargine. Chances Of Having Resistance?

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Posted on Thu, 22 Aug 2013
Question: Am adult onset Type I Diabetic. Well controlled on Novolog & Glargine. Recently Glargine does not seem to be working as it has in the past. Is it possible to develop resistance to Lantus or is there a history of loss of effectiveness over time?
doctor
Answered by Dr. Nsah Bernard (2 hours later)
Hello,

Thanks for posting,

Resistance to injection insulin (lantus/insulin glardin) is extremely rare. You will first of all need to consider dosage first before thinking of resistance. Maybe if your doctor increase the dosage of glardine, then your diabetes might be able to be controlled. Also, it is possible too that with increasing age, you might have developed Type II Diabetes which will require other forms of treatment rather than the one you have been on through out your life.
It will be best to discuss this with your treating physician and he can then establish a much more recent recommendation for you.

Hope this helps and wish you the best.
Dr. Nsah
Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar
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Follow up: Dr. Nsah Bernard (1 hour later)
Thank you Dr. XXXXXXX I had considered Type II or 1.5 a as I have heard it called. I appreciate your time.
XXXXXXX Salveson
doctor
Answered by Dr. Nsah Bernard (8 minutes later)
Hello XXXXXXX

You are welcome and wish you the best and a better health.

Dr. Nsah
Note: For further follow up on related General & Family Physician Click here.

Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar
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Answered by
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Dr. Nsah Bernard

General & Family Physician

Practicing since :2012

Answered : 1704 Questions

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Diabetic, Taking Novolog & Glargine. Chances Of Having Resistance?

Hello,

Thanks for posting,

Resistance to injection insulin (lantus/insulin glardin) is extremely rare. You will first of all need to consider dosage first before thinking of resistance. Maybe if your doctor increase the dosage of glardine, then your diabetes might be able to be controlled. Also, it is possible too that with increasing age, you might have developed Type II Diabetes which will require other forms of treatment rather than the one you have been on through out your life.
It will be best to discuss this with your treating physician and he can then establish a much more recent recommendation for you.

Hope this helps and wish you the best.
Dr. Nsah