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Di agonized for Lever Cancer, suggested Sorafenat. Done CT scan. recommend treatment?

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Oncologist, Surgical
Practicing since : 2004
Answered : 59 Questions
Hi my father has been diagonized for Lever Cancer .CT scan report attached ,He has been suggested for tablet Sorafenat . Composition of tablet is sorafenib
Our Doctor has suggested that it can't be cured now and rest at home is preferable along with relatives.We want him to lead the painless life without any complications and pain.So far he is ok . Please suggest whether he can take the recommended medicine and also suggest things we need to take care so that he can lead painless life.Normally how long such patients can survive ?
Posted Thu, 10 Oct 2013 in Colon Cancer
Answered by Dr. Krishna Kiran Kannepalli 13 hours later
Brief Answer:
Sorafenib will help. Good diet is essential.

Detailed Answer:

Thanks for the query.

As the reports suggest your father has an advanced liver cancer. Treatment modalities such as surgery, liver transplantation, radio frequency ablation are not suitable in this situation. Trans arterial chemo embolisation is also not possible as there is portal vein thrombosis and as the disease has spread to the lungs. The only option is Sorafenib.

This is only aimed at reducing the symptoms by reducing the tumor burden and is not for curing the disease. If pain is a significant symptom not relieved with oral medications, take care of his diet. Protein supplements will help.

The average survival is around 8-10 months, but if sorafenib works (it works in 27-40% of patients), the life expectancy may increase by another 4-6 months. A supportive and encouraging family is the need of the hour.

Best wishes
Above answer was peer-reviewed by
Follow-up: Di agonized for Lever Cancer, suggested Sorafenat. Done CT scan. recommend treatment? 8 hours later
Thanks a lot Dr XXXXXXX for reply .My father has started Sorafenib .
Could you please explain the term "celiac plexus block" (sentence mentioned in your reply ). It will help me to understand the things completely.
Answered by Dr. Krishna Kiran Kannepalli 19 minutes later
Brief Answer:
Blocks pain nerves from the abdominal organs.

Detailed Answer:
Celiac plexus is located in the upper abdomen around the aorta. It carries pain sensation from organs such as liver, stomach, pancreas. When there is excessive pain due to cancer, chemical agents are injected into the plexus either by a percutaneous route or via an endoscopic route. This will destroy the celiac plexus and the patient will not have perception of pain. This is an established form of treatment for patients suffering from advanced cancer.
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