Can Typhoid Fever Relapse Post Recovery?
Typhoid fever -probably relapse
Detailed Answer:
Hi,
Thank you for your query. I can understand your concerns.
Up to 10% of patients with Typhoid fever develop mild relapse, usually within 2–3
weeks of fever resolution and in association with the same strain type
and susceptibility profile.
Relapse is managed with a similar (10-14 days) or abbreviated course (5-7 days) of the same therapy (antibiotics) used in the initial episode.
Many patients excrete S. typhi in their stools or urine for some days after starting antibiotic treatment. Convalescent carriers excrete for periods up to 3 months.Faecal carriage is more frequent in individuals with gallbladder disease and is most common in women over 40.
Your mom might be a chronic carrier.
Do an Ultra-sonography of abdomen to exclude gall bladder disease.
Two typhoid vaccines are commercially available: (1) Ty21a, an
oral live attenuated S. typhi vaccine (given on days 1, 3, 5, and 7, with
a booster every 5 years); and (2) Vi CPS, a parenteral vaccine consisting
of purified Vi polysaccharide from the bacterial capsule (given in
a single dose, with a booster every 2 years).
However in endemic areas( like most of the sates in XXXXXXX ), the cumulative efficacy is 48% for Ty21a at 2.5–3.5 years and 55% for Vi CPS at 3 years.
Efficacy rates of Typhoid Vaccine to prevent Typhoid fever may be even lower in certain endemic areas.
Regards
Dr. T.K. Biswas M.D. XXXXXXX