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Can severe prolonged stress cause peptic ulcer in stomach?

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General Surgeon
Practicing since : 2008
Answered : 1290 Questions
Hi my name is Kim, and I was wondering is you could get and ulcer from having so much stress in your life?
Posted Sat, 8 Feb 2014 in Digestion and Bowels
Answered by Dr. Ashish Verma 33 minutes later
Brief Answer: yes surely it can Detailed Answer: Hi XXXXXXX Thanks for writing to XXXXXXX This is Dr. Ashish Verma, a general surgeon, answering to your query. Yes severe prolonged stress is known to cause peptic ulcer in stomach, and this has been conclusively proven in various studies. The major effects of stress on gut physiology include: 1) alterations in gastrointestinal motility; 2) increase in visceral perception; 3) changes in gastrointestinal secretion; 4) increase in intestinal permeability; 5) negative effects on regenerative capacity of gastrointestinal mucosa and mucosal blood flow; and 6) negative effects on intestinal microbial flora. Hope i have answered all your queries. If you have further queries, i will be glad to answer them. Regards Dr. Ashish Verma
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