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Can Polyethylene Glycol Cause Weight Gain?

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Posted on Thu, 31 Jul 2014
Question: Dear Dr. I've been taking polyethylene glycol 3350, 17 grams twice a day in the AM/PM time of day per my doctors advice for my GI issues/bleeding hemirriods, because I strain rectally. I've been on this dose for about 10 to 12 days now. I did get my internal hemrriods treated and my rectal bleeding has greatly been reduced. However, I still strain going but not as much. My question is, with respect to my dosage of polyethylene glycol 3350 17 grams x 2 a day, I have gained about 10 lbs. during this period of time. Can polyethylene glycol 3350 cause this unwanted body fluid weight gain? I watch my weight very closely, and I beleive it has a lot to do with this side effect, it seems so timely during this particular time. Thank you, and looking forward to hearing from you.
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Answered by Dr. Dr. Klerida Shehu (11 hours later)
Brief Answer:
Yes,might be polyethylen glycol side effect..

Detailed Answer:
Hi,

You are reporting to be using polyethylene glycol 3350 for about 12 days now and have gained weight.

Now, please bare in mind that water retention and edema in the extremities (swollen feet) is one of the rare effects of using polyethylene glycol 3350.

This explains why you have gained weight during this period (also called fluid weight gain).

I recommend to discuss this side effect with your doctor in order to change therapy.

Hope it was of help! Let me know if you have further questions!
Dr.Klerida
Note: For further follow up on digestive issues share your reports here and Click here.
Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar
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Answered by
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Dr. Dr. Klerida Shehu

Gastroenterologist

Practicing since :2006

Answered : 2266 Questions

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Can Polyethylene Glycol Cause Weight Gain?

Brief Answer: Yes,might be polyethylen glycol side effect.. Detailed Answer: Hi, You are reporting to be using polyethylene glycol 3350 for about 12 days now and have gained weight. Now, please bare in mind that water retention and edema in the extremities (swollen feet) is one of the rare effects of using polyethylene glycol 3350. This explains why you have gained weight during this period (also called fluid weight gain). I recommend to discuss this side effect with your doctor in order to change therapy. Hope it was of help! Let me know if you have further questions! Dr.Klerida