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Can S-Adenosylmethionine Be Taken Along With Alendronic Acid, Pantoprazole, Levothyroxine, Fenofibrate And Atorvastatin?
Question: I would like to get advise from a kidney specialist , hope you can advise me .
I would like to take s-adenosylmethionine for my osteoarithritis . i am of 76 years of age and am on :
actrapid (insulin) alendronic acid 70mg ,
Adcal d3 bd, mycophenolate 500mg bd, tacrolimus 1mg bd, levothyroxine 25mcg od, atorvastatin 10mg od, dustatseride 0.5mg od, bethanechol25mcg tds fenofibrate 160mg od, diltiazem 120mg od, pantoprazole 20mg od, prednisilone 10mg
i will discuss with the consultant that i am going to take it once I decides to after consulting a kidney specialist . However I would be grateful if you could let me know if you believe it could be possibly safe to take and what precautions is required such as any monitoring .
I would like to take s-adenosylmethionine for my osteoarithritis . i am of 76 years of age and am on :
actrapid (insulin) alendronic acid 70mg ,
Adcal d3 bd, mycophenolate 500mg bd, tacrolimus 1mg bd, levothyroxine 25mcg od, atorvastatin 10mg od, dustatseride 0.5mg od, bethanechol25mcg tds fenofibrate 160mg od, diltiazem 120mg od, pantoprazole 20mg od, prednisilone 10mg
i will discuss with the consultant that i am going to take it once I decides to after consulting a kidney specialist . However I would be grateful if you could let me know if you believe it could be possibly safe to take and what precautions is required such as any monitoring .
Brief Answer:
S adenosylmethionine is considered safe
Detailed Answer:
Hi
Thanks for posting your query on HealthcareMagic. I am a Clinical Pharmacologist and will try to assist you as best as I can within my specialty.
It is widely taken for osteoarthritis. Most studies on S-adenosyl methionine consider it as a safe adjunct to non steroidal anti inflammatory drugs. Its efficacy in osteoarthritis and side effect profile are considered less than these pain killers.
One isolated study in cisplatin treated mice showed its harmful effect on kidneys. In these mice both Blood urea nitrogen and serum creatinine raised steadily. But its effect on human kidneys is lacking.
As precaution you may regularly track the levels of BUN and Serum creatinine. Though it can also be measured by special tests like HPLC, such tests are usually only available for research purposes.
Theoretically it may increase metabolism of some drugs thus their blood levels and efficacy may decrease.
As such, most supplements are not well studied. Thus they may have known or unknown side effects.
If you really need to take it, you can try it in lower doses.
Hope it helps. Let me know if I can assist you further.
Dr Vaishalee
S adenosylmethionine is considered safe
Detailed Answer:
Hi
Thanks for posting your query on HealthcareMagic. I am a Clinical Pharmacologist and will try to assist you as best as I can within my specialty.
It is widely taken for osteoarthritis. Most studies on S-adenosyl methionine consider it as a safe adjunct to non steroidal anti inflammatory drugs. Its efficacy in osteoarthritis and side effect profile are considered less than these pain killers.
One isolated study in cisplatin treated mice showed its harmful effect on kidneys. In these mice both Blood urea nitrogen and serum creatinine raised steadily. But its effect on human kidneys is lacking.
As precaution you may regularly track the levels of BUN and Serum creatinine. Though it can also be measured by special tests like HPLC, such tests are usually only available for research purposes.
Theoretically it may increase metabolism of some drugs thus their blood levels and efficacy may decrease.
As such, most supplements are not well studied. Thus they may have known or unknown side effects.
If you really need to take it, you can try it in lower doses.
Hope it helps. Let me know if I can assist you further.
Dr Vaishalee
Note: For further queries related to kidney problems and comprehensive renal care, talk to a Nephrologist. Click here to Book a Consultation.
Above answer was peer-reviewed by :
Dr. Chakravarthy Mazumdar
Answered by
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