Brief Answer:
They can be used simultaneously if needed.

Detailed Answer:
Hello and thanks for using HCM.

I have read your question and understand your concerns.

Both, cyclizine and metoclopramide are drugs that are used to treat nausea and vomiting.

Cyclizine is an antihistaminic drug, metoclopramide belongs to antidopaminergic/antiserotoninergic drugs, so, their mechanism of action is different and they can be used together, if it is very necessary to use both of them. Please let me know the indication you are using them for.

Hope you found the answer helpful.

Let me know if I can assist you further.

Greetings.

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Brief Answer:
Some antagonist interaction may happen.

Detailed Answer:
Welcome back.

Best thing about controlling nausea and vomiting is to use first only one drug.

Again, cyclizine and ondansetron act with different mechanisms, but some antagonistic reaction may result.

This issue should be discussed with your treating Doctor, he can decide if it is worth clinically to use both drugs, only for a short time.

Hope this helps.

Best regards.

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