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Can Amitriptyline And Phenergan Be Taken Together?

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Posted on Tue, 9 Dec 2014
Question: can amitriptylines be mixed with phenergan
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Answered by Dr. Seikhoo Bishnoi (21 minutes later)
Brief Answer:
If possible should be avoided

Detailed Answer:
Hello Thanks for asking from HCM

Phenargan (promethagine) causes sedation and amitriptyline also causes sedation. If both drugs are used together then severe sedation and drowsiness are seen.

Also use of phenargan with amitriptyline will increase the risk of its anti-cholinergic side effects as drowsiness, giddiness, blurred vision, constipation, dry mouth symptoms.

As per my opinion the drugs should not be mixed together or should be used with caution in low doses only.

Thanks, hope this helps you.

You can ask again if you have more questions.
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Above answer was peer-reviewed by : Dr. Bhagyalaxmi Nalaparaju
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Answered by
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Dr. Seikhoo Bishnoi

Psychiatrist

Practicing since :2007

Answered : 5193 Questions

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Can Amitriptyline And Phenergan Be Taken Together?

Brief Answer: If possible should be avoided Detailed Answer: Hello Thanks for asking from HCM Phenargan (promethagine) causes sedation and amitriptyline also causes sedation. If both drugs are used together then severe sedation and drowsiness are seen. Also use of phenargan with amitriptyline will increase the risk of its anti-cholinergic side effects as drowsiness, giddiness, blurred vision, constipation, dry mouth symptoms. As per my opinion the drugs should not be mixed together or should be used with caution in low doses only. Thanks, hope this helps you. You can ask again if you have more questions.