Brief Answer:
You will not tox out on that dose

Detailed Answer:
Good afternoon. My name is Dr. Saghafi and I am a neurologist with this network.

The 15mg. you mention I assume is per SERVING (which the label will specify; either a teaspoon, 1/2 teaspoon, tablespoon, etc.). Toxicity symptoms from pyridoxine are not believed to occur in most people until they exceed 200 mg. at one time. The FDA as of 2003 determined that the upper limit for most people should be 100mg./day although some countries and standards have recommended the maximum daily limit to be no more than 50mg.

The RDA for pyridoxine is 1-2 mg. daily for adults. You should be aware that the RDA does not represent what people SHOULD BE INGESTING in order to get optimal effects from any nutrient. They are giving us the numbers which represent the MINIMUM amount that our bodies need just to stay even with normalcy and not fall into deficiency states which can then, cause pathological states to occur.

Therefore, I would say that although 15 mg. SOUNDS like a lot when you compare that to the RDA...the actual amount you ingest just through daily foods and assuming you are healthy and have no organ dysfunction could very well be very close to the 15mg. level so if you take this supplement then, that still only puts you at 30mg. day which is well below the USFDA's upper limit of 100mg. Bottom line is that you should have nothing to worry about with your supplement in terms of B6 or B12 for that matter.

There is also a certain amount of the B complex vitamins which are automatically excreted through the kidneys and so it is actually very hard for most people to intentionally overdose just by eating normal foods and even if they take supplements. By the way, I am aware of the fact that you have some cystic formations in your kidneys but am not impressed with that condition enough to worry about how they would handle the excretion of something like B6 or B12.

I will reserve my opinion on this or other supplements in general which are advertised for promoting BRAIN POWER since you didn't ask.

I hope these answers satisfactorily addresses your question. If so, may I ask your favor of a HIGH STAR RATING with some written feedback?

Also, if there are no other questions or comments, may I ask you CLOSE THE QUERY on your end so this question can be transacted and archived for further reference by colleagues as necessary?

Please direct more comments or inquiries to me in the future at:

bit.ly/drdariushsaghafi

I would be honored to answer you quickly and comprehensively.

Please keep me informed as to the outcome of your situation.

The query has required a total of 39 minutes of physician specific time to read, research, and compile a return envoy to the patient.

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Brief Answer:
Nutritional Supplementation without scientific evidence of effects

Detailed Answer:
My opinion on "brain power" supplements? Well, I'll tell you that our knowledge of dietary substances which have been PROVEN to be beneficial to maintaining healthy brain function and optimal performance is EXTREMELY LIMITED. There is some knowledge available on foods, vitamins, and some minerals which we know clearly are quite necessary for the brain to function at optimal levels such as B12, Folate, and probably Vit. D. Vit. E used to be in that mix but we've since backed off to the Fish Oil compounds since Vit. E in some people is contraindicated be cause take blood thinners and the combination of Vit. E and those medications is risky. Fish Oil is a risk as well in terms of combining with some blood thinners, however, we believe it's less.

However, that sort of information is DIFFERENT from what the Nutrient Supplement Industry wants to get out there as their message which is full of misleading information and at times out and out lies.

And so the bottom line in my opinion is this....while certain nutrients and substances are quite necessary for optimal brain health...there is no consistent scientific evidence down long term on at risk populations to show that a person is already eating a healthy diet and living a good lifestyle (no smoking, controlling hypertension, diabetes, exercising adequately, etc.) will gain any ground by taking nutritional supplements in the name of "boosting brain power" or "protecting Neurons from the effects of Alzheimer's disease" or anything even remotely similar to that. The very best thing that one can do for their brains is to continuously work the organ just like a muscle. Stay healthy and do all the things to stay that way without spending money, time, and believing in false advertising that this food or that food will change your brain chemistry to the point where you will avoid or beat out whatever the genetic program is which is built into the DNA.

Even high level thinking types of activities and full out taking advantage of cultural events and knowing how to speak 5 languages or being in the busiest of work climates and managing 10 things at once is not a guarantee that one will not develop dementia. Taking tons of brain supplements isn't going to change that equation and the proof of that would be all the patients and their families who I've seen through the years get hung up on spending all their monies on these things which don't ever amount to anything at all.

Healthy and Active Lifestyle with minimizing risks from things clearly DETRIMENTAL to the body. Getting good rest, having a lifestyle as trimmed down from unnecessary or destructive forces of stress, learning new things as you get older and staying PHYSICALLY FITTER THAN you can imagine...and then, consuming the brain FOODS...the naturally occurring, freshly prepared brain FOODS is where you'd be best spending your money.....you'll keep your heart and kidneys healthy and that automatically keeps your brain healthy.

Supplements are entirely UNNECESSARY and a waste of good time and money that can be much better spent helping your kids with school projects or going out and running a few miles...even if you have arthritis.....

Now you know my opinion on Brain Power Supplements. You cannot delay the onset of anything...not even the common cold by taking that material. You're simply making other people rich and taking away precious resources you should be using on yourself and your family.

Remember, if something is that easy...it's probably not the best way to do something complex...don't you tell your kids that? Nothing wrong with taking supplements if a person TRULY NEEDS them because of a measured and known deficiency due to an illness, a malfunctioning organ system, or some other unforeseen situation or circumstance. But with everything I've mentioned there's is no way I would believe a person should be deficient or lacking in any major nutritional element necessary for good and optimal brain health. Therefore, supplementation is superfluous.

I hope this little rant has given you at least a different perspective. If you feel that you can't embrace everything I've said...trust me...I wouldn't be offended..we are all raised in environments and we have points of view which take years to formulate, usually after a lot of training and conditioning. To suddenly change one's mind for an opposite philosophy is one of the hardest things that a person can do.....All the best.

I hope these answers satisfactorily addresses your question. If so, may I ask your favor of a HIGH STAR RATING with some written feedback?

Also, if there are no other questions or comments, may I ask you CLOSE THE QUERY on your end so this question can be transacted and archived for further reference by colleagues as necessary?

Please direct more comments or inquiries to me in the future at:

bit.ly/drdariushsaghafi

I would be honored to answer you quickly and comprehensively.

Please keep me informed as to the outcome of your situation.

The query has required a total of 65 minutes of physician specific time to read, research, and compile a return envoy to the patient.

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Brief Answer:
Thank you for your kind words

Detailed Answer:
It is a pleasure answering questions for folks who have an open mind and are willing to consider other points of view when it comes to such topics. Many are not as open and as a result can be taken advantage of by large industries who have built monumental empires from going AGAINST common sense and convincing their clients that they should buy products that make no sense at all knowing that they have so much better to choose from provided by what's already been provided in the form of natural (but I mean really naturally occurring) foodstuffs!

Perhaps, tech support can help you attach the rating before you close out....it would be so greatly appreciated if your rating could be aggregated. But if not, I understand.

Please do not hesitate to contact me again at: bit.ly/drdariushsaghafi for additional questions or concerns. Cheers.

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