White matter

What is White matter?

White matter is tissue found in the brain. It contains nerve fibers. Many of these nerve fibers (axons) are surrounded by a type of fat called myelin. The myelin gives the white matter it's color. Myelin acts as an insulator. It plays an important role in the speed of nerve signaling.

Questions and answers on "White matter"

what is on A MRI ? I have a lot of white matter?

doctor1 MD


Hi,

An MRI obtains images of body organs by making use of magnetic waves. What organs are visualized on an MRI depends on the site of the imaging.

No one ever has excess white matter. We may have areas where white matter is lost but never the contrary. I will suggest that you upload the entire...

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what does chronic infraction and mild chronic white matter microvascular ischemic disease mean?

doctor1 MD

Brief Answer:
ischemia- reduced blood supply, infarction- died off because of less blood

Detailed Answer:
HI, thanks for using healthcare magic

Ischemia/ischemic disease means that there is reduced supply to an area. Infarction means that reduced blood supply to an area has caused it to die off/...

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Is there a brain abnormality that begins with white?

All I need to know are brain abnormalities that begin with the word white. I can look up symptoms and implications elsewhere. She is my dearest friend and I am worried.

doctor1 MD

Brief Answer:
You are probably talking about white matter lesions.

Detailed Answer:
Hi Gthomas,
Thanks for being on healthcaremagic.com.
I am Dr.Ajay Panwar,a neurologist,here to answer your query.

You are probably referring to 'white matter lesion' or 'white matter disease' or 'white matter changes...

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what does a mri show when a lot of white matter and no one told me anything else but it is 200 pages long?

doctor1 MD


Thank you for posting your query.

I am Dr Sudhir Kumar, Neurologist, and I would try my best to help you.

I have noted your details. Based on this, I would like to say that white matter is normally present in brain and it would be visible on MRI too. What we need to know is that- whether the...

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Hello. I've had spasmodic dysphonia for 3 years. All of the usual treatments have been ineffective (Botox, speech therapy, etc) so I've been reviewing research on the pathophysiology of SD in my spare time.

I recently came across this: http://m.brain.oxfordjournals.org/content/131/2/447

I'm hoping a neurologist can explain what this means in simpler terms: "DTI showed right-sided decrease of fractional anisotropy in the genu of the internal capsule and bilateral increase of overall water diffusivity in the white matter along the corticobulbar/corticospinal tract in 20 spasmodic dysphonia patients compared to 20 healthy subjects."

Is this saying that some brain tissue connectivity was different in SD patients?

Also, I recently had an MRI indicating that I have mild white matter disease. Could this white matter disease be an indication of similar abnormalities as found in the research's DTI results?

Thank you in advance.

doctor1 MD

Brief Answer:
Yes, white matter changes probably related to Spasmodic Dysphonia (SD).

Detailed Answer:
Hello and thanks for using HCM.

I have read your question and understand your concerns.

Genu of the internal capsule, cortico-bulbar and cortico-spinal tracts are all white matter structures of...

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Can you please advise if there could be a correlation between dizziness and nausea symptoms and the "only" remarkability on exam (physical neuro exam was unremarkable) of note was the the MRI showed a "mild degree of chronic white matter changes"

doctor1 MD

Brief Answer:
Hypertension, Old Head Injury, Marijuana Usage may be causing the symptoms

Detailed Answer:
Hi,

Welcome to HealthCareMagic.com I am Dr.J XXXXXXX Anto Bruno Mascarenhas, and I am here to help you. I have read your question with care and understand that you want to know the...

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Yes, please. I do have a VP Shunt - installed from having a massive subarachnoid hemmorage in 1997. Been having a lot of problems lately - ;ast 5 or 6 years or so and they are getting worsed...nausea, headaches in the back of my skull where the valve was put in, tenderness, lethargy, tired, pain down my right quadrant. We cannot locate anyone in the area willing to do a shunt o gram. Is it true that as long as I am not vomitting I should be ok? Is there anything else I could check for myself to ensure it's not a VP Malfunction? Too much pressure in the back of my skull and pain, tenderness at the valve entry point. I am not feeling well at all...been queasy off and on for at least a week. I am feeling a salty taste going down my throat, but no coughing . But my abdomen hurts - stings, actually on my right side. So does the area where the valve was inserted. I feel like something may be infected or perhaps over/underdraining. Help, please?

I've already had two MRI's indicating the ventricles are slit. My Neuro says I have White Matter Disease now & edema. I am also having problems with my balance (disequilibrium), hearing & some blurred vision. And understanding spoken conversations. It's all intermittent. I have been very sleepy latelty and very disinterested in everything - that is unusual for me. I rarely leave the house.
It is difficult for me to organize my thoughts to get anything accomplished at all.

Sorry, didn't see the Medications Tried - Gabapentin (for feelings of electric shocks throughout my right side of body & head, however it hurt my stomach & I stopped taking it. Lyrica for pain. Hydrocodone for pain (stopped taking it). Valium for the Severe Tinnitus (stopped taking that also - made me too drowsy). They did try me on ADHD meds to help my thinking, and it does, however I'm concerned about my blood pressure so I've backed off that for now. Am taking Enalapryl & Amilodipine for hypertension also. They tried NSAIDS for pain however that gave me heartburn so I stopped those.

doctor1 MD

Brief Answer:
Infection can be easily ruled out by local examination.

Detailed Answer:
Hello,

Thank you for posting your query. I have seen the reports and read through your query carefully.

The location of shunt placement could be infected, but can be easily found out by a simple clinical...

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I am a 50 yr old white female. Diagnosed with Trigeminal and Occipital neuralgia and undefined facial pain. Gabapentin was started and dc'd due to allergic reaction. Baclofen was then introduced and tolerated well at 10 mg/3x daily. Occipital flares have occurred 2x in Dec with one resulting in an ER visit and intravenous dilaudid introduced, two doses within an hour a part. Minimized but never diminished pain. I did have an MRI 10/4/06 when findings state: "Brain parenchyma shows a few scattered areas of increased signal intensity in the white matter that are felt to be nonspecific in nature. There are no mass lesions, extra-axial fluid collections, hemorrhage or other pathologic signal intensities. The ventricular system is of normal size and appearance. The pituitary gland is normal. Posterior fossa structures show a vascular structure at adjacent to the lateral portion of the left trigeminal nerve as it enters the brain stem. It appears to cause some compression of the trigeminal nerve."

Impression: 1. Vascular structure adjacent to the proximal portion of the left trigeminal nerve. This does appear to cause some distortion of the left trigeminal nerve. 2. Nonspecific white matter changes in both hemispheres.

My concern is the burning I have in my upper left, toward back of skull area. This is constant. The other symptom is nasal congestion that occurs with EXCESSIVE sneezing that is disruptive during the day and night. Decongestant tabs and loratadine is does not elicit a response from this symptom. Are there things that can occur simultaneously with TN and ON that can cause this anomaly and is white matter a concern? This does elevate my bp to 158/101 when I am a normal 117/70. thank you so much for your time!

doctor1 MD

Brief Answer:
White matter changes probably due to blood pressure changes.

Detailed Answer:
Hello and thanks for using HCM.

I have read your questions and understand your concerns, seen the attached image,

The burning on the area of skull you describe is most likely caused by Occipital neuralgia...

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mri scan showed . no diffusion restriction to suggest acute infarct. Mild T2 / flair signal hyperintensities in periventricular white matter, probable incidental small vessel ischemic changes. No suprasellar mass.

doctor1 MD

Brief Answer:
High blood pressure issues.

Detailed Answer:
Hello and thanks for using HCM.

I have read your question and understand your concerns.

Periventricular small white matter changes may indicate small artery disease of brain.

These findings suggest a narrowing of these arteries due to not...

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In reading a MRI report, I noticed that the impression was that there was an interval progression of mild patchy areas of white matter signal abnormality, nonspecific but possibly secondary to accelerated chronic microvascular ischemia. The concern that I have was it noted the progression over the short period of time (approximately 5 months), was somewhat unexpected. There was a significant head injury not quite 2 years earlier. Could the head injury have any bearing on the white matter signal abnormality?

doctor1 MD

Brief Answer:
Head trauma is not responsible for those changes.

Detailed Answer:
Hello and thanks for using HCM.

I have read your question and understand your concerns.

Trauma is not a common cause of nonspecific white matter changes, especially if it was a minor head injury, so, other possible...

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Recent questions on  White matter

doctor1 MD

what does a mri show when a lot of white matter and no one told me anything else but it is 200 pages long?

doctor1 MD

what is on A MRI ? I have a lot of white matter?

doctor1 MD

I had an MRI W/o contrast three years ago and it foundscattered white matter flairhyperintensities indicating a demyelinating processes such as inflammatory, infectious and vascultic- just had mri w and w/o contrast found multiple nodules of...

doctor1 MD

Hi,

I would like to know the meaning of the following:

MR Scan of brain reveals normal grey-white matter differentiation of both cerebral hemisphere. There are patchy white matter hyperintense foci on T2 weighted sequence in the perpendicular & subcortal white matter of both cerebral hemispheres. These lesion are iso-to hypointense on T1 & bright on FLAIR sequence. None of these lesions are bright on diffusion sequence. These features are consistent with chronic white matter ischaemic changes due to small vessel arteriosclerotic changes. No mass effect / midline shift seen. bilateral basal ganglia are normal.

Apart from this cerebellar hemispheres & brainstem, internal auditory canal & its content, ventricular system, sellar and parasellar regions, and calvarium are mentioned as normal.

I would appreciate the meaning of this. Please reply in English.

Thanks,
Greg

doctor1 MD

Brain scan report states: There are a few patchy hypo densities in the white matter of the cerebral hemispheres which are non specific. Also: minimal white matter changes that likely represent early or minimal ischemic changes. What does all this mean?

doctor1 MD

Hello I had a MRI conclusion is Multival small T2/Flair hyperintence signal areas inbilalateral cerebral white matter with sparing of corpus callosum. Most liklly due to chronic small vessel iscaemic changes.the cerebral white matter prodomenly in frontoparietal lobes with sparing of the corpus callosum and the subcortical U fibres.I have never had blood pressure,smoked a little when young,very little.I eat pretty well ,and do moderate exercise.Will I have a stroke from this,how can I prevent that.Or am I heading foe dementia.I am 60 next yr and am female.I do have truble processing what people say,and can t process too much at once.I have pretty much always had this. Could you kindly give me an answer.Thanks Paula.

doctor1 MD

i m 48 years old with MRI finding that says several tiny T2 hyperintense foci noted in the white matter of the frontal lobes bilaterally in keeping with minimal chronic microangiopathic ischemic white matter changes. Impression: minimal chronic microangiopathic ischemic white matter changes. Is this something to worry about?

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