Thrombus

What is Thrombus?

A thrombus, or colloquially a blood clot, is the final product of the blood coagulation step in hemostasis. There are two components to a thrombus: aggregated platelets that form a platelet plug, and a mesh of cross-linked fibrin protein. The substance making up a thrombus is sometimes called cruor. A thrombus is a healthy response to injury intended to prevent bleeding, but can be harmful in thrombosis, when clots obstruct blood flow through healthy blood vessels.

Mural thrombi are thrombi that adhere to the wall of a blood vessel. They occur in large vessels such as heart and aorta, and can restrict blood flow but usually do not block it entirely. They appear grey-red with alternating light and dark lines (known as lines of Zahn) which represent bands of fibrin (lighter) with entrapped white blood cells and red blood cells (darker).

Questions and answers on "Thrombus"

I was diagnosed with DVT 6 months ago after I tore a calf muscle (gastrocnemius - moderate to severe tear). I am currently on Warfarin , and my...

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Human chorionic gonadotropin (HCG) is used for female infertility and other conditions resulting from a lack of this hormone and more...

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Hi 2weeks ago my husband suffered epigastric pain, when they did the ECG there s a little abnormality, they do also do the blood test for troponin...

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Atypical chest pain or epigatric pain with abnormal ECG needs to be corelated clinically if Troponin I is high . Even if Echo and Angigram is...

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I was diagnosed with DVT & PE 2 weeks ago. After 9 days of Coumadin therapy I have swelling & soreness of the ankle/heel area. X-rays confirmed...

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Hello and welcome to HCM,

Swelling and pain in the ankle/ heel region with ahistory of DVT suggests that these symptoms are most probably due to...

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