Immunosuppression

What is Immunosuppression?

Immunosuppression involves an act that reduces the activation or efficacy of the immune system. It is done by Immunosuppressive drugs or immunosuppressive agents or antirejection medications are drugs that inhibit or prevent activity of the immune system.

Questions and answers on "Immunosuppression"

Hi my son has post transplant lymphoproliferative disease following 10 years of immunosuppression after heart transplant. he has been treated for with ritiximub for what they think but cant confirm b cell mediated. we had a pet scan a week ago and he now has a red spot within his bowel that has shown up. we have had biopsys taken. what possible diagnosis could we be facing

doctor1 MD

Hello,

Hot spot in the abdomen of pet scan in an immunosuppressed patient may be due to tubercular lymphadenitis or reactive lymphadenitis or cytomegalovirus infection or lymphoma etc.

Please consult your doctor treating doctor and do ultrasound abdomen if necessary CT scan of the abdomen. Then...

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my husband has been a kidney transplant patient two years ago , recently he is suffering from severe diarrhea which improved after lacteol forte but new red rashes appear on his back and stomach, he is equivocal for CMV IGm and currently elevated serum creatinine level 1.92 , any advice since am not able to reach his doctor now

doctor1 MD

Hi,
CMV at this stage of Transplant is less likely since immunosuppression is at minimum at this stage ( assuming it was reduced to minimum dosages). Besides, CMV IgM is not a good test to detect CMV infection after the transplant. Granted that, it is a good test before the transplant.
Would...

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Am suffering from fungal infection from past 3 months on my vaginal part and on my face near nose and eyes part one of the doctor suggested me to go with lecivent cream and candid-b for private parts itching has not happening but still with face wt to do if any ayurvedic pl suggest me and i want to get rid of this and i want know does it affect pregnancy as we r planning for this

doctor1 MD

Hi
welcome to HCM
Though candida infecton is common in vagina, it is not that frequent on the face, unless there is an immunosuppression. Visit to a lab where there is facility for diagnosis of cutaneous infection to get it confirmed. It may turn out to be a dermatophyte infection.

Raw garlic and...

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Hi,
Does the Rabipur vaccine works on a hiv patient ?

doctor1 MD

Hi XXXXXXX

Thanks for your query.

Individuals with immunosuppression and HIV infection (regardless of CD4 count) should be given Rabipur. Rabipur is life saving in AIDS patients when the CD4 counts are low and sero conversion is compromised.

If you have any more queries, feel free to ask.

Regards...

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Does i pill is safe for kidney transplant patient

doctor1 MD

Brief Answer:
Should be avoided

Detailed Answer:
Dear Friend

I pill contains a hormone levonorgestrel. It has been implicated in many studies to cause renal problems , in people who are already at high risk like diabetics , hypertensives.
Since you had a damage and you got new transplanted...

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Dear Dr. how are you PLS can some one help me I m Muhanad From Iraq I have AS Ankylosing Spondylitis my doctor tell me to take medicine called salazopyrin 500mg but when I start to take it it cause for me Breathing difficulties I start by 1g daily (one pill twice ) is that normal or it is some thing wrong? or it must stop this medicine please help me

doctor1 MD

Hi welcome to HCM,
The first symptoms Ankylosing Spondylitis are typically chronic pain and stiffness in the middle part of the spine or sometimes the entire spine, often with pain referred to one or other buttock or the back of thigh from the sacroiliac joint.,which may itself present as...

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For Female Age 47 tested RA -Negative And ACCP ratio Negative priscriped ONCOTREX 10mg and FOLVITE once in a week along with LEFNO 20mgandZY-Q 200mg Tablets daily after food. Will there be any adverse side effects in the future if what could be the side effects?
Complaints: Sweeling and paining of all the joints and both the toes

doctor1 MD

Hello,

Thanks for posting your query.

You have been prescribed disease modifying agents for polyarthralgia. If these drugs are taken for a long term they do have side effects like oral ulcers, recurrent infections, immunosuppression, anaemia, pigmentations, hair fall, weight loss, nausea,...

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I just found out I have oral linchen planus and Iam on a steriod cream, for my mouth, I also have found out I have vulvovaginal gingival syndrome and It all seems so grime. I would like to know if there is anything other than steroids, creams out there? Also just how bad is lp/ vuvlovaginal gingival sydrome, I am pretty scared and need more information, can home remeties help and what are some if they exsist? I was told wants u have this condition you will always have it, is this true? Can a change of diet help, also I only have one kidney do to kideny cancer, so I have to be very careful in health or health relative problems. Thanks

doctor1 MD

Hello ,
Thanks for the query

Immunosuppression causes aggravation of these kind of diseases where there is desquamation of mucosa and skin.

Since you had kidney cancer you must be on chemotherapeutic drugs which might have aggravated the disease.

Patients with vulvavaginal syndrome will have...

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Here is a pic white tongue goes but not fully when scraped an comes back.

doctor1 MD

Brief Answer:
Scrapable plaques odds for candida

Detailed Answer:
Hi,

I read your query and I want to reassure you that Many white lesions involving the oral mucosa are benign and do not require treatment.

-have you used broad-spectrum antibiotics or corticosteroids in recent past?
-Did you use...

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I have been give a total of 4 steroid injections since July, my last injection was Oct 12, then I was given a medrol dose pack the following week and stopped taking them after 2 days due to numbness of the lips (took benadryl for the reaction). My question is how long does this steroid use decrease your immune system? My granddaughter got the flu last night and wondering if my chances of contacting it is greater (I was not around her yesterday) but there is a baby shower at their house today?

doctor1 MD

Hi, thank you for the query. Steroid is used primarily for it's immunosuppresive or anti-inflammatory role. Now the question is, Does this immunosuppression can cause someone to get flu ? The answer is it might be "Yes". But that is not the doctor's concern. Medically significant immunosuppression...

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Recent questions on  Immunosuppression

doctor1 MD

I had a double bypass in 2001. For the last few days I have had a very uneasy shaky feeling inside, sort of like when your sugar level drops low, but I can tell that it isnt my sugar. I have also felt very tired, almost to the point that it is an effort to walk very far. I have several other heath issues (psoriatic arthritis, severe psoriasis, thyroid tumor and the list goes on) and have not maintained a healthy lifestyle. Although I do take my medications regularly and watch what I eat, I do not exercise and I started back smoking. I recently started on Pravastatin and I was already on Lisinopril. I also take Enbrel injections. Could any of these medications be causing me to feel this way? Or could it be that the bypass has blockages and needs to be done again?

doctor1 MD

My wife suffers from illness after much diagnosis identifies as Psoriasis Rheumatoid Arthritis and has been on Wysone of 10mg per tablet per day with a weekly drug of Methotrexate..( which she now tapering owing to slightly elevated liver issue).. My wife is unable to do away with wysolone which she says is a wonder drug for her because it gives her instant relief..SHE is AWARE of the long term consequences but insists that TODAY is important than ONLY tomorrow.. IS there a Solution in Homeopathy so that I can wean her away from Wysolone pl.. Anxious husband

doctor1 MD

Hi, I am on cyclosporin for psoriasis. Started 1 1/2 weeks ago. Dose is low (150 mg) daily: I weigh 150 lbs. I feel fine but have noticed slight difficulty swallowing liquids and my urine is darker and poss a bit cloudy. I was prescribed by a dermatologist , my next appointment is in 6 weeks ( though have blood tests 2 weekly). My question is are these side effects a problem ie should I get in touch with doctor or are they ok. Also can you drink alcohol on cyclosporin. I can t find an answer definitively!

doctor1 MD

Hello Sir, My mother is suffering from Cardiomegaly . Her case history is, she has chronic rheumatoid arthritis and she is taking leflunomide , methatroxate and some steroids. Now, in the recent X-ray , it is found that she has cardiomegaly(mild). How dangerous is it and what is the treatment and life expectancy and what care should be taken for this. I am in Australia and planning to call her over here, can I? Thanks Heaps! Kind Regards, Bhaumik

doctor1 MD

Hello Doctors, my father is suffering from psoriasis for the past 3 years, he is 77years old. Whether it is advisable to take oncotrex tab (2.5 mg 3/Week) ? need your suggestions on this.. i was told that this medicine has side effects , has some...

doctor1 MD

Hi,what is actual treatment given to vitiligo over lips(not on lips) in 11 years,as in can topical psoralen be added with topical steroid ,,(2) how is vitiligo over elbow treated in a 11 years old,as in is topical psoralen applied daily in 11...

doctor1 MD

Gd mrng,sir,,may be this is my 7 th time query to you,ill be prescise so that i get a precise answer,my 11 year old son,developed three hypopigmented patches on rt elbow,i consulted to some top dermats in my city,who said it was post inflammatory...

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