Haptocorrin

What is Haptocorrin?

Haptocorrin also known as transcobalamin-1 (TC-1) is a protein that in humans is encoded by the TCN1 gene. The essential function of haptocorrin is protection of the acid-sensitive vitamin B12 while it moves through the stomach.

Haptocorrin (HC), also commonly known as the R-protein, or the R-factor, or previously referred to as transcobalamin I, is a unique glycoprotein produced by the salivary glands of the oral cavity, in response to ingestion of food. This protein binds strongly to vitamin B12 in what is perhaps an intricate yet necessary evolutionary mechanism to protect this vitamin from the acidic environment of the stomach.

Questions and answers on "Haptocorrin"

Hi I was wondering what an increasing vitamin b12 level (now about 800) means in relation to an acute or chronic worry of family members, in an...

doctor1 MD

Brief Answer:
Useful only is diagnosis, no prognostic value

Detailed Answer:
Hi,
I am Dr. Prakash HM and I would like to answer your query.
High...

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First of all i don't know which category question is this that i am going to ask.
My age is 25 , single height is 5,11 weight is 51 kg only.
i want...

doctor1 MD

Hello,
Thanks for posting your query.

I can understand your concern for weight gain. Sometimes malbasorption syndrome can cause less weight gain....

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I am 32, weight 11s9lb, height 5ft5".
I went to the docs the other day as I have not had a period since Feb 11th, one before that was start of Dec...

doctor1 MD

Hi,

I understand that you are facing a multitude of health issues and trying to find out the best reason for the same. Most often it is not right...

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Recent questions on  Haptocorrin

doctor1 MD

Hello Doctor, I am having Acid Reflux Issue(GERD). I have tested my blood for VitaminD, Liver Function Test. VitaminD is 10.5 and Vitamin B12 is...

doctor1 MD

I note a LOT of b12 issues, yet no answers like, perhaps it's pernicious anemia. ( For us non- Dr.'s it's a form of anemia that keeps you from...

doctor1 MD

Hi I was wondering what an increasing vitamin b12 level (now about 800) means in relation to an acute or chronic worry of family members, in an...

doctor1 MD

my mother agd 75 has a vertigo problem. particulaly when she lies down and she gets up. she feels dizzy at that time mostly. She has started vertin...

doctor1 MD

I have a spastic duodenal cap. In 2004, I was told that I had pernisious anemia that developed over three years. My stomach can t absorb vitamin...

doctor1 MD

I just want to know about b12 ... i am vegitirian how to increase my b12 .,, last some days i suffered pain in my leg and i feel tired... i doubt...

doctor1 MD

is lack of vitamin b causes stress or stress causes lack of vitamin b ?

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