What is Zoladex?

Goserelin acetate (Zoladex, AstraZeneca) is an injectable gonadotropin releasing hormone superagonist (GnRH agonist), also known as a luteinizing hormone releasing hormone (LHRH) agonist. Structurally, it is a decapeptide. Goserelin acetate is used to suppress production of the sex hormones (testosterone and estrogen), particularly in the treatment of breast and prostate cancer.

Goserelin acetate stimulates the production of the sex hormones testosterone and estrogen in a non-pulsatile (non-physiological) manner. This causes the disruption of the endogenous hormonal feedback systems, resulting in the down-regulation of testosterone and estrogen production.

Zoladex was approved by the U.S. Food and Drug Administration in 1989 for treatment of prostate cancer.

Questions and answers on "Zoladex"

I have done a laparoscopy 3yrs ago, d endometrioma returned, I was place on zoladex for 3mths and d cyst decreased significantly, 1yr later d cyst...

doctor1 MD

Hi there ~

There are many other treatments for endometrioma and I would strongly advise you to take a second opinion for the symptoms you are...

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Sir, i am 28 year old girl and i am suffering from endometriosis. I am unmarried and i do not want surgery because some doctors say it is risky for...

doctor1 MD

Thanks for writing to Health Care Magic
Zoladrex injection also has severalside-effects. A laparoscopic sugery will probably be a better option....

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