What is Zoely?
Nomegestrol acetate (INN; Lutenyl), or 19-normegestrol acetate, is a steroidal progestin with additional antigonadotropic effects which was introduced in 1986 and is used as a hormonal contraceptive. Unlike many other steroidal progestogens, it is selective for the progesterone receptor, lacking any significant affinity for other steroid receptors such as the androgen, estrogen, glucocorticoid, and mineralocorticoid receptors. As a result, it does not possess any androgenic, estrogenic, glucocorticoid, or mineralocorticoid effects. However, at sufficiently high doses it does have potent antiestrogenic and antiandrogenic effects due to its progesterone receptor-mediated antigonadotropic properties.