What is Ziac?

Hydrochlorothiazide (abbreviated HCTZ, HCT, or HZT), is a diuretic medication often used to treat high blood pressure and swelling due to fluid build up. Other uses include diabetes insipidus, renal tubular acidosis, and to decrease the risk of kidney stones in those with high calcium level in the urine. For high blood pressure it is often recommended as a first line treatment. HCTZ is taken by mouth and may be combined with other blood pressure medications as a single pill to increase the effectiveness.

Potential side effects include poor kidney function, electrolyte imbalances especially low blood potassium and less commonly low blood sodium, gout, high blood sugar, and feeling faint initially upon standing up. While allergies to HCTZ are reported to occur more often in those with allergies to sulfa drugs this association is not well supported. It may be used during pregnancy but is not a first line medication in this group.

It is in the thiazide medication class and acts by decreasing the kidneys' ability to retain water. This initially reduces blood volume, decreasing blood return to the heart and thus cardiac output. Long term, however, it is believed to lower peripheral vascular resistance.

Two companies, Merck and Ciba, state they discovered the medication which became commercially available in 1959. It is available as a generic drug and is not very expensive.

Questions and answers on "Ziac"

I have high blood pressure I take 20 mg. a day of Lisinipril and I was taking 5mg of ziac. However, my prescription company won't pay for the ziac...

doctor1 MD

Yes , it reduce both blood pressure as well as palpitation and high heart beat
You can continue it
Hope this will help
Dr Alok

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Started taking the druc Bisoprolo (Ziac) approx 10 months ago and am now having problems with ED. I have no problem getting a erection at the...

doctor1 MD

Hi welcome to HCM...

Yes you are right....Beta blocker drugs like bisoprolol can lead erectile dysfunction ..

If you have high blood pressure or...

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My wife takes ziac 10-6.25mg in the morning and lisinopril 20mg in the afternoon but her blood pressure is still 140-150 over 90. Should she take...

doctor1 MD

Brief Answer:
The dose of Lisinopril may be increased

Detailed Answer:
Dear Sir,

I would advise her to take another 10 mg Lisinopril in the...

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