What is Tiazac?

Diltiazem (INN) () is a nondihydropyridines (non-DHP) calcium channel blocker used in the treatment of hypertension, angina pectoris, and some types of arrhythmia. It relaxes the smooth muscles in the walls of arteries, which opens (dilates) the arteries, allows blood to flow more easily, and lowers blood pressure. Additionally, it lowers blood pressure by acting on the heart itself to reduce the rate, strength, and conduction speed of each beat.

It is also used off-label as an effective preventive medication for migraine. It is a class 3 antianginal drug, and a class IV antiarrhythmic. It is a common adulterant of cocaine seized in the UK, and has been found to reduce cocaine cravings in rats, indicating it may prolong the "high" (see below).

Diltiazem is metabolized by and acts as an inhibitor of the CYP3A4 enzyme which can cause it to interact with a variety of other medications.

Questions and answers on "Tiazac"

I just switch from Tiazac 240 mg to Tiazac XC 360 mg. I used to take Tiazac 240 in the morning with my breakfast. I now have to take Tiazac XC...

doctor1 MD

Hi friend,
Welcome to Health Care Magic

It is an extended release formulation - it can be taken at any time.

Take care
Wishing speedy recovery

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What is the difference between Tiazac XC and metoprolol tartrate. I have been on metoprolol for 5 years but I am having a little trouble with my...

doctor1 MD


Welcome to XXXXXXX

Metoprolol is a beta adrenergic receptor blocking agent. It reduce blood pressure by reducing heart rate.

Decrease in...

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Is there an association between tiazac and nightmares? Currently on tiazac, synthroid, flomax, avodart. Slow heart rate low 40s most of time,...

doctor1 MD


Thanks for your query.

I can feel your concerns .

There is no association of tiazac with nightmares.
Yes, sleep apnea has strong association...

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