What is Talwin?

Pentazocine is a synthetically-prepared prototypical mixed agonist–antagonist narcotic (opioid analgesic) drug of the benzomorphan class of opioids used to treat moderate to moderately severe pain. Pentazocine is sold under several brand names, such as Fortral, Sosegon, Talwin NX (with the μ-antagonist naloxone, will cause withdrawal in opioid dependent persons on injection), Talwin, Talwin PX (without naloxone), Fortwin (Lactate injectable form) and Talacen (with acetaminophen). This compound may exist as one of two enantiomers, named (+)-pentazocine and (−)-pentazocine. (−)-pentazocine is a κ-opioid receptor agonist, while (+)-pentazocine is not, instead displaying a ten-fold greater affinity for the σ receptor. Usually, in its oral formulations, it is combined with naloxone so as to prevent people from crushing the tablets, dissolving them in a solvent (like water) and injecting them for a high (as naloxone is not orally bioavailable it produces no effect when the formulation is used orally, but it blocks the opioid effects of pentazocine if injected intravenously for a high). Related drugs include phenazocine, dezocine, cyclazocine and several chemicals used in research on the central nervous system.

Questions and answers on "Talwin"

Has Watson stopped making pentezocine naloxone {talwin nx} ? or stopped distribution in XXXXXXX ?

doctor1 MD

Brief Answer:
Probably its a distribution issue

Detailed Answer:
Thanks for choosing health care magic for posting your query.
I have gone...

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I have severe chronic lower back pain originating from a car accident and am allergic to codeine, torodol, talwin. I am presently using tramacet...

doctor1 MD

Brief Answer:
Combination drug and Tricyclic antidepressants

Detailed Answer:
Welcome to Healthcare-Magic
Greetings of the day


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I've been takeing Talwin for over thirty years and now my pharmacy is saying they are having trouble getting it. Is there a reason they would be...

doctor1 MD

Brief Answer:
old drug and not used frequently

Detailed Answer:
Hello and thanks for your question.
As you know there has been a lot of problems...

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