What is Sulfatrim?
Trimethoprim/sulfamethoxazole (TMP/SMX) or co-trimoxazole (BAN) is an antibiotic used to treat a variety of bacterial, fungal, and protozoal infections. It consists of one part trimethoprim to five parts sulfamethoxazole. The drug has been marketed worldwide in generic preparations and under multiple brand names, including Septra (GlaxoSmithKline plc) and Bactrim (Hoffmann-La Roche). Co-trimoxazole is generally considered bactericidal, although its components are individually bacteriostatic. It is an antifolate drug, and functions by inhibiting both de novo folate biosynthesis and metabolism.
Common side effects of TMP/SMX include nausea, vomiting and diarrhoea. Its use near the end of pregnancy is not recommended.
It is on the World Health Organization's List of Essential Medicines, the most important medications needed in a basic health system.
Trimethoprim/sulfamethoxazole is often abbreviated as SXT, TMP-SMX, TMP-SMZ, or TMP-sulfa, although the abbreviating of drug names is not best practice in medicine.