Stilbestrol

What is Stilbestrol?

Diethylstilbestrol (DES, former BAN stilboestrol) is a synthetic nonsteroidal estrogen that was first synthesized in 1938. It is also classified as an endocrine disruptor. Human exposure to DES occurred through diverse sources, such as dietary ingestion from supplemented cattle feed and medical treatment for certain conditions, including breast and prostate cancers. From about 1940 to 1971, DES was given to pregnant women in the mistaken belief it would reduce the risk of pregnancy complications and losses.

In 1971, DES was shown to cause clear cell carcinoma, a rare vaginal tumor in girls and women who had been exposed to this drug in utero. The United States Food and Drug Administration subsequently withdrew DES from use in pregnant women. Follow-up studies have indicated that DES also has the potential to cause a variety of significant adverse medical complications during the lifetimes of those exposed. The United States National Cancer Institute recommends women born to mothers who took DES undergo special medical exams on a regular basis to screen for complications as a result of the drug. Individuals who were exposed to DES during their mothers' pregnancies are commonly referred to as "DES daughters" and "DES sons".

Questions and answers on "Stilbestrol"

Hi, We want a "best guess" Expected period of survival? Should another blood test (psa) be done immediately...was this a mistake /error? sholud he...

doctor1 MD

You can opt for Homoeopathic mode of management.As Homoeopathy is side effectless and very mild to act in oncological cases where immunity gets...

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I was sexually active until the late 1970's. Didn't find my permanent pal. Some vaginas were smooth, hard-walled, and lacked folds, or any...

doctor1 MD

Brief Answer:
Oestrogen deficiency causes these symptoms

Detailed Answer:
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Vaginal changes are age dependent....

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doctor1 MD

Hi, We want a best guess Expected period of survival? Should another blood test (psa) be done immediately...was this a mistake /error? sholud he...

doctor1 MD

Hi. I was sexually active until the late 1970's. Didn't find my permanent pal. Some vaginas were smooth, hard-walled, and lacked folds, or any...

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