Singulair

What is Singulair?

Montelukast (trade names Singulair or Pluralair, Montecarlo-10, and Montecarloflo and Lovetas in India) is a leukotriene receptor antagonist (LTRA) used for the maintenance treatment of asthma and to relieve symptoms of seasonal allergies. Montelukast is usually taken once a day with or without food. Montelukast is a CysLT1 antagonist; it blocks the action of leukotriene D4 (and secondary ligands LTC4 and LTE4) on the cysteinyl leukotriene receptor CysLT1 in the lungs and bronchial tubes by binding to it. This reduces the bronchoconstriction otherwise caused by the leukotriene and results in less inflammation.

Because of its method of operation, it is not useful for the treatment of acute asthma attacks. Again because of its very specific mechanism of action, it does not interact with other asthma medications such as theophylline.

Another leukotriene receptor antagonist is zafirlukast (Accolate). Zileuton (Zyflo), an asthma drug, blocks leukotriene synthesis by inhibiting 5-lipoxygenase, an enzyme of the eicosanoid synthesis pathway.

The Mont in Montelukast stands for Montreal, the place where Merck developed the drug.

Questions and answers on "Singulair"

I have pain in the left side of my throat when I swallow (not all the time but off and on) for the past few days and I felt a small moveable lump...

doctor1 MD

CLERITIN D IS A BAD COMBINATION AS IT DECONGESTS AND DRIES UP THE TRACT OF OROPHARYNX AND LOWER TRACTS
THS CAUSES THE PROBLEMS WRITTEN BY YOU...

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Hello Dr, My Toddler is now 20 months old boy and gets wheezing from his 9months and am advised to use Nebuliser - (Asthalin Respiratory Solution...

doctor1 MD

Namasthe
Welcome to Healthcare-Magic
Greetings of the day

Giving Alex p will suffice
I would also advise the following
1. Normal saline...

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Recent questions on  Singulair

doctor1 MD

Hi I saw my doctor on Monday for a cough resulting from my allergies and post nasal drip. He's has added singulair to my current meds (5mg Zrtec...

doctor1 MD

Hello Dr, My Toddler is now 20 months old boy and gets wheezing from his 9months and am advised to use Nebuliser - (Asthalin Respiratory Solution...

doctor1 MD

I have bouts of severe tightness in neck , pressure in head, always on left side. Interfering with work as cannot think straight, have nausea and...

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